质量水平
方案
97%
mp
317 °C (dec.) (lit.)
官能团
amide
SMILES字符串
NC(=O)c1cccc(n1)C(N)=O
InChI
1S/C7H7N3O2/c8-6(11)4-2-1-3-5(10-4)7(9)12/h1-3H,(H2,8,11)(H2,9,12)
InChI key
UUVCRNTVNKTNRK-UHFFFAOYSA-N
一般描述
2,6-吡啶二甲酰胺是一种优异的过渡金属三齿配体(Cu2+,Ni2+)。
应用
2,6-吡啶二甲酰胺可用于制备基于Sn-卟啉衍生物的新型分子旋转栅。
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Aurélie Guenet et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 17(23), 6443-6452 (2011-04-22)
The design, synthesis and structural characterisation, in solution, of two new molecular turnstiles based on Sn-porphyrin derivatives are described. The system is composed of a stator (5-(4-pyridyl)-10,15,20-triphenylporphyrin), a hinge (Sn(IV)) and a rotor (handle equipped with 2,6-pyridinedicarboxamide as a tridentate
Victor Maurizot et al.
Chemical communications (Cambridge, England), (8)(8), 924-925 (2004-04-08)
A heptameric amide of 2,6-diaminopyridine and 2,6-pyridinedicarboxylic acid coordinates to Cu(II) to assemble into a double helical complex with a string of six shortly spaced Cu ions.
Synthetic ion transporters can induce apoptosis by facilitating chloride anion transport into cells.
Sung-Kyun Ko et al.
Nature chemistry, 6(10), 885-892 (2014-09-23)
Anion transporters based on small molecules have received attention as therapeutic agents because of their potential to disrupt cellular ion homeostasis. However, a direct correlation between a change in cellular chloride anion concentration and cytotoxicity has not been established for
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