方案
99.999%
浓度
50 wt. % in H2O
沸点
107 °C
密度
1.078 g/mL at 25 °C
SMILES字符串
NO
InChI
1S/H3NO/c1-2/h2H,1H2
InChI key
AVXURJPOCDRRFD-UHFFFAOYSA-N
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一般描述
羟胺溶液广泛用作有机合成、聚合物行业和水处理领域中的还原剂和抗氧化剂。
应用
作为制备下列化合物的反应物:
- 心血管药物 Nω-羟基-L-精氨酸(NOHA,一氧化氮前体)的前药
- 羟基氨基胍,作为抗癌药
- 非甾体2,3-二氢喹啉糖皮质激素受体激动剂,具有降低的磷酸烯醇丙酮酸羧基激酶(PEPCK)转录激活活性
- 氧氟沙星的羧酰胺衍生物,具有改善的抗菌特性
- 基于香豆素类似物的TNF-α转化酶(TACE)抑制剂
- HIV整合酶抑制剂
羟胺溶液(NH2OH)可作为反应物用于制备:
- 来自醛类的伯酰胺,通过芳烃钌(II)络合物催化。
- 羟基氨基胍和生物研究用氧氟沙星的甲酰胺衍生物。
- 用于抗体固定化的Fe3O4/Au (GoldMag)纳米颗粒。
警示用语:
Danger
危险分类
Acute Tox. 4 Oral - Aquatic Acute 1 - Carc. 2 - Desen. Expl. 4 - Eye Dam. 1 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 - STOT SE 3
靶器官
Blood, Respiratory system
储存分类代码
3 - Flammable liquids
WGK
WGK 3
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Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
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