467995
噻唑烷-2-甲酸
97%
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关于此项目
经验公式（希尔记法）:
C4H7NO2S
化学文摘社编号:
分子量:
133.17
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
97%
InChI
1S/C4H7NO2S/c6-4(7)3-5-1-2-8-3/h3,5H,1-2H2,(H,6,7)
SMILES string
OC(=O)C1NCCS1
InChI key
ULSZVNJBVJWEJE-UHFFFAOYSA-N
assay
97%
mp
176 °C (lit.)
functional group
carboxylic acid, thioether
Quality Level
General description
噻唑烷-2-羧酸 (β-噻脯氨酸) 是脯氨酸类似物。它是β-内酰胺抗生素的重要组成部分。目前其X射线光电子能谱已经过研究。有报道称，它是猪肾脏D-氨基酸氧化酶的生理底物。噻唑烷-2-羧酸可以由半胱胺和乙醛酸酯合成。
Application
噻唑烷-2-羧酸可用于氮杂双环加合物和5-芳基-2,3-二氢吡咯并[2,1-b]噻唑-6,7-二甲醇6,7-双(异丙基氨基甲酸酯)的合成。
signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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C Foppoli et al.
The Italian journal of biochemistry, 30(5), 355-366 (1981-09-01)
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W M Frederiks et al.
The Histochemical journal, 25(8), 578-582 (1993-08-01)
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L Włodek et al.
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Synthesis and chromatographic properties of selenazolidine-2-carboxylic acid (beta-selenaproline).
C De Marco et al.
The Italian journal of biochemistry, 28(2), 104-110 (1979-03-01)
商品
Proline analogues are promising candidates for tuning the biological, pharmaceutical, or physicochemical properties of naturally occuring, as well as de novo designed, linear, and, cyclic peptides.
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