471429
(S)-(-)-α-氨基-γ-丁内酯 氢溴酸盐
99%
别名:
L-高丝氨酸内酯 氢溴酸盐
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关于此项目
经验公式（希尔记法）:
C4H7NO2 · HBr
化学文摘社编号:
分子量:
182.02
UNSPSC Code:
12352005
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3912375
Assay:
99%
Form:
solid
Quality Level
assay
99%
form
solid
optical activity
[α]20/D −21°, c = 1 in H2O
mp
225 °C (dec.) (lit.)
functional group
ester
storage temp.
2-8°C
SMILES string
Br[H].N[C@H]1CCOC1=O
InChI
1S/C4H7NO2.BrH/c5-3-1-2-7-4(3)6;/h3H,1-2,5H2;1H/t3-;/m0./s1
InChI key
MKLNTBLOABOJFZ-DFWYDOINSA-N
Application
制备用于法尼基蛋白转移酶 以及硒代甲硫氨酸 的假肽抑制剂。
(S)-(-)-α-Amino-γ-butyrolactone hydrobromide may be used as a building block to prepare:
- β-ketoamide N-acylated-L-homoserine lactones (AHLs) as quorum sensing molecules
- p-coumaroyl-HSL (homoserine lactone)
- calpain and lipid peroxidation inhibitors
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Novel dual inhibitors of calpain and lipid peroxidation.
Auvin S, et al.
Bioorganic & Medicinal Chemistry Letters, 14(14), 3825-3828 (2004)
Koch, T. Buchardt, O.
Synthesis, 1065-1065 (1993)
A new class of homoserine lactone quorum-sensing signals.
Schaefer AL, et al.
Nature, 454(7204), 595-599 (2008)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 471429-5G | 04061832360010 |