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经验公式(希尔记法):
C8H6BrN
化学文摘社编号:
分子量:
196.04
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
96%
Form:
solid
产品名称
7-溴吲哚, 96%
InChI
1S/C8H6BrN/c9-7-3-1-2-6-4-5-10-8(6)7/h1-5,10H
SMILES string
Brc1cccc2cc[nH]c12
InChI key
RDSVSEFWZUWZHW-UHFFFAOYSA-N
assay
96%
form
solid
mp
41-44 °C (lit.)
functional group
bromo
Quality Level
Application
7-Bromoindole may be used in the synthesis of the following:
- indole
- dyestuffs
- 8-bromocarboline
General description
7-Bromoindole is a 7-substituted indole derivative. Its synthesis from 7-bromoindole-2-carboxylic acid has been reported. It has been reported to reduce the production of staphyloxanthin in Staphylococcus aureus.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
Total synthesis of indoles from Tricholoma species via Bartoli/heteroaryl radical methodologies.
A Dobbs
The Journal of organic chemistry, 66(2), 638-641 (2001-06-30)
Zhiqian Wang et al.
Tetrahedron letters, 53(5), 477-479 (2012-05-01)
A novel MCAP-cycloaddition sequence has been applied to the facile synthesis of β-carboline intermediates to gain rapid access to novel derivatives of yohimbine-like and corynanthe-like compounds that may be easily diversified by cross-coupling reactions and N-derivatizations to generate small compound
The structure of monobrominated ethyl indole-3-carboxylate and the preparation of 7-bromoindole.
Leggetter BE and Brown RK.
Canadian Journal of Chemistry, 38(9), 1467-1471 (1960)
Jin-Hyung Lee et al.
Applied microbiology and biotechnology, 97(10), 4543-4552 (2013-01-16)
Human pathogens can readily develop drug resistance due to the long-term use of antibiotics that mostly inhibit bacterial growth. Unlike antibiotics, antivirulence compounds diminish bacterial virulence without affecting cell viability and thus, may not lead to drug resistance. Staphylococcus aureus
J Y Kim et al.
Letters in applied microbiology, 41(2), 163-168 (2005-07-22)
To establish multicomponent phenol hydroxylases (mPHs) as novel biocatalysts for producing dyestuffs and hydroxyindoles such as 7-hydroxyindole (7-HI) from indole and its derivatives. We have isolated Pseudomonas sp. KL33, which possesses a phenol degradation pathway similar to that found in
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