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Merck
CN

475394

Sigma-Aldrich

2-(2-溴乙氧基)四氢-2H-吡喃

96%

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关于此项目

经验公式(希尔记法):
C7H13BrO2
化学文摘社编号:
分子量:
209.08
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
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方案

96%

包含

~1% K2CO3 as stabilizer

折射率

n20/D 1.482 (lit.)

沸点

62-64 °C/0.4 mmHg (lit.)

密度

1.384 g/mL at 25 °C (lit.)

SMILES字符串

BrCCOC1CCCCO1

InChI

1S/C7H13BrO2/c8-4-6-10-7-3-1-2-5-9-7/h7H,1-6H2

InChI key

GCUOLJOTJRUDIZ-UHFFFAOYSA-N

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一般描述

2-(2-Bromoethoxy)tetrahydro-2H-pyran is an organic building block. It has been synthesized by employing 2-bromoethanol as a starting reagent.

应用

用于制备心磷脂类似物的 2-羟乙基衍生物、呋喃-稠合化合物、吲哚和吡唑。
2-(2-Bromoethoxy)tetrahydro-2H-pyran may be used in the synthesis of:
  • 4-(2-chloroethoxy)benzenesulfonyl chloride
  • estrogen ligands bearing carborane
  • 2-(2-(1,3-di((E)-2-(2-(2-(2-(5-(4-(tert-butoxycarbonyl(methyl)amino)styryl)pyridin-2-yloxy)ethoxy)ethoxy)ethoxy)ethoxy)propan-2-yloxy)ethoxy)-tetrahydro-2H-pyran

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

190.4 °F - closed cup

闪点(°C)

88 °C - closed cup

个人防护装备

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Stacy W Remiszewski et al.
Journal of medicinal chemistry, 46(21), 4609-4624 (2003-10-03)
A series of N-hydroxy-3-phenyl-2-propenamides were prepared as novel inhibitors of human histone deacetylase (HDAC). These compounds were potent enzyme inhibitors, having IC(50)s < 400 nM in a partially purified enzyme assay. However, potency in cell growth inhibition assays ranged over
Zhihao Zha et al.
Journal of medicinal chemistry, 54(23), 8085-8098 (2011-10-21)
β-Amyloid plaques (Aβ plaques) in the brain are associated with cerebral amyloid angiopathy (CAA). Imaging agents that could target the Aβ plaques in the living human brain would be potentially valuable as biomarkers in patients with CAA. A new series
Y Endo et al.
Chemistry & biology, 8(4), 341-355 (2001-04-28)
Carboranes (dicarba-closo-dodecaboranes) are a class of carbon-containing polyhedral boron-cluster compounds having remarkable thermal stability and exceptional hydrophobicity. Applications of the unique structural and chemical properties offered by icosahedral carboranes in boron neutron capture therapy have received increasing attention over the
Heterocycles, 62, 207-211 (2004)
Synlett, 1404-1404 (2006)

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