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Merck
CN

47637

Fmoc-Trp-OH

≥97.0% (HPLC)

别名:

Fmoc-L-色氨酸

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关于此项目

经验公式(希尔记法):
C26H22N2O4
化学文摘社编号:
分子量:
426.46
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352200
EC Number:
252-706-5
MDL number:
Beilstein/REAXYS Number:
4216624
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InChI key

MGHMWKZOLAAOTD-DEOSSOPVSA-N

InChI

1S/C26H22N2O4/c29-25(30)24(13-16-14-27-23-12-6-5-7-17(16)23)28-26(31)32-15-22-20-10-3-1-8-18(20)19-9-2-4-11-21(19)22/h1-12,14,22,24,27H,13,15H2,(H,28,31)(H,29,30)/t24-/m0/s1

SMILES string

OC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OCC3c4ccccc4-c5ccccc35

assay

≥97.0% (HPLC)

optical activity

[α]20/D −29±1°, c = 1% in DMF

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

mp

182-185 °C (lit.)

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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Chloé Guilbaud-Chéreau et al.
ACS applied materials & interfaces, 11(14), 13147-13157 (2019-03-14)
Molecular gels formed by the self-assembly of low-molecular-weight gelators have received increasing interest because of their potential applications in drug delivery. In particular, the ability of peptides and amino acids to spontaneously self-assemble into three-dimensional fibrous network has been exploited
Devi Wahyuningtyas et al.
Chembiochem : a European journal of chemical biology, 20(16), 2133-2140 (2019-06-06)
Huntington's disease (HD) is classified as a protein-misfolding disease correlated with the mutant Huntingtin (mHtt) protein with abnormally expanded polyglutamine (polyQ) domains. Because no effective drugs have yet been reported, attempts to develop better therapy to delay the age of
Chiao-Ting Yen et al.
European journal of medicinal chemistry, 44(5), 1933-1940 (2008-12-27)
Twenty-four new dipeptide analogs (1-24) of aurantiamide acetate were designed, synthesized, and assayed for effects on superoxide anion generation and elastase release by human neutrophils in response to fMLP/CB. Among them, seven N-(fluorenyl-9-methoxycarbonyl) (Fmoc)-dipeptides (6, 9, 12, 14, 17, 18

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