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经验公式(希尔记法):
C26H22N2O4
化学文摘社编号:
分子量:
426.46
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352200
EC Number:
252-706-5
MDL number:
Beilstein/REAXYS Number:
4216624
InChI key
MGHMWKZOLAAOTD-DEOSSOPVSA-N
InChI
1S/C26H22N2O4/c29-25(30)24(13-16-14-27-23-12-6-5-7-17(16)23)28-26(31)32-15-22-20-10-3-1-8-18(20)19-9-2-4-11-21(19)22/h1-12,14,22,24,27H,13,15H2,(H,28,31)(H,29,30)/t24-/m0/s1
SMILES string
OC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OCC3c4ccccc4-c5ccccc35
assay
≥97.0% (HPLC)
optical activity
[α]20/D −29±1°, c = 1% in DMF
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
mp
182-185 °C (lit.)
application(s)
peptide synthesis
functional group
Fmoc
storage temp.
2-8°C
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
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Huntington's disease (HD) is classified as a protein-misfolding disease correlated with the mutant Huntingtin (mHtt) protein with abnormally expanded polyglutamine (polyQ) domains. Because no effective drugs have yet been reported, attempts to develop better therapy to delay the age of
Chiao-Ting Yen et al.
European journal of medicinal chemistry, 44(5), 1933-1940 (2008-12-27)
Twenty-four new dipeptide analogs (1-24) of aurantiamide acetate were designed, synthesized, and assayed for effects on superoxide anion generation and elastase release by human neutrophils in response to fMLP/CB. Among them, seven N-(fluorenyl-9-methoxycarbonyl) (Fmoc)-dipeptides (6, 9, 12, 14, 17, 18
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