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经验公式(希尔记法):
C24H21NO5
化学文摘社编号:
分子量:
403.43
UNSPSC Code:
12352200
NACRES:
NA.26
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3573123
产品名称
Fmoc-Tyr-OH, ≥97.0% (HPLC)
InChI
1S/C24H21NO5/c26-16-11-9-15(10-12-16)13-22(23(27)28)25-24(29)30-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22,26H,13-14H2,(H,25,29)(H,27,28)/t22-/m0/s1
SMILES string
OC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)OCC2c3ccccc3-c4ccccc24
InChI key
SWZCTMTWRHEBIN-QFIPXVFZSA-N
assay
≥97.0% (HPLC)
optical activity
[α]20/D −22±2°, c = 1% in DMF
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
application(s)
peptide synthesis
functional group
Fmoc
storage temp.
2-8°C
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Chiao-Ting Yen et al.
European journal of medicinal chemistry, 44(5), 1933-1940 (2008-12-27)
Twenty-four new dipeptide analogs (1-24) of aurantiamide acetate were designed, synthesized, and assayed for effects on superoxide anion generation and elastase release by human neutrophils in response to fMLP/CB. Among them, seven N-(fluorenyl-9-methoxycarbonyl) (Fmoc)-dipeptides (6, 9, 12, 14, 17, 18
Weidang Wu et al.
Cancer science, 106(6), 747-756 (2015-04-14)
L-type amino acid transporter 1 (LAT1), overexpressed on the membrane of various tumor cells, is a potential target for tumor-targeting therapy. This study aimed to develop a LAT1-mediated chemotherapeutic agent. We screened doxorubicin modified by seven different large neutral amino
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