方案
98%
mp
118-120 °C (lit.)
官能团
amide
hydroxyl
SMILES字符串
NC(=O)CO
InChI
1S/C2H5NO2/c3-2(5)1-4/h4H,1H2,(H2,3,5)
InChI key
TZGPACAKMCUCKX-UHFFFAOYSA-N
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一般描述
甘氨酰胺是甘氨酸的异构体，可以通过乙醇酸乙酯的氨解来合成。已有研究报道了乙醇酰胺的构象分析。已有研究测定了其在水中的扩散系数和部分摩尔等温压缩性。人们研究了其热力学性质。人们已测得了其渗透压和活度系数。
应用
乙醇酰胺可用于制备磷酸甘油酰胺。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Parmeshwari K Halen et al.
Mini reviews in medicinal chemistry, 9(1), 124-139 (2009-01-20)
Non-steroidal anti-inflammatory drugs (NSAIDs), commonly used for the treatment of chronic inflammatory diseases suffer from several undesired side effects, the most important being gastrointestinal (GI) irritation and ulceration. The prodrug designing is one of the several strategies used to overcome
Partial molal isothermal compressibility of glycine, DL-α-alanine, glycylglycine, glycolamide, and lactamide.
Yayanos AA.
The Journal of Physical Chemistry, 97(49), 13027-13028 (1993)
Fereidoon Daryaee et al.
European journal of medicinal chemistry, 44(1), 289-295 (2008-04-26)
On the basis of the structural similarity of N-substituted glycolamides with N-glycolyl muramic acid residues of the cell wall of Mycobacterium tuberculosis, a series of these compounds were designed and synthesized by the reaction of glycolic acid acetonide 1 (2,2-dimethyl-5-oxo-1,3-dioxolane)
P R Brown et al.
Journal of general microbiology, 133(6), 1527-1533 (1987-06-01)
A positive selection is described for isolating amidase-negative mutants from Pseudomonas aeruginosa strains. The method is based on the conversion, via amidase activity, of glycollamide to glycollate which is growth inhibitory. Three types of mutant were isolated on lactate medium
A K Bansal et al.
Drug development and industrial pharmacy, 27(1), 63-70 (2001-03-15)
Glycolamide esters of ibuprofen (I), namely, unsubstituted (II), N,N dimethyl (III), and N,N diethyl (IV), were synthesized and studied for different physicochemical, pharmacological, and toxicological properties. They were comparable with I in respect of anti-inflammatory and analgesic activity but did
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