485896
L-Asparagine-(amide-15N) monohydrate
98 atom % 15N
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线性分子式:
H215NCOCH2CH(NH2)CO2H · H2O
化学文摘社编号:
分子量:
151.13
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.12
产品名称
L-Asparagine-(amide-15N) monohydrate, 98 atom % 15N
SMILES string
O.N[C@@H](CC([15NH2])=O)C(O)=O
InChI
1S/C4H8N2O3.H2O/c5-2(4(8)9)1-3(6)7;/h2H,1,5H2,(H2,6,7)(H,8,9);1H2/t2-;/m0./s1/i6+1;
InChI key
RBMGJIZCEWRQES-UEFLAVRISA-N
isotopic purity
98 atom % 15N
form
solid
optical activity
[α]20/D +31.5°, c = 1 in 1 M HCl
mp
233-235 °C (lit.)
mass shift
M+1
Quality Level
相关类别
Packaging
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Jun Wu et al.
Nature cell biology, 23(1), 75-86 (2021-01-10)
Nutrient availability is central for T-cell functions and immune responses. Here we report that CD8+ T-cell activation and anti-tumour responses are strongly potentiated by the non-essential amino acid Asn. Increased Asn levels enhance CD8+ T-cell activation and effector functions against
Longfei Deng et al.
Nature communications, 11(1), 1755-1755 (2020-04-11)
Asparagine synthetase (ASNS) catalyses the ATP-dependent conversion of aspartate to asparagine. However, both the regulation and biological functions of asparagine in tumour cells remain largely unknown. Here, we report that p53 suppresses asparagine synthesis through the transcriptional downregulation of ASNS
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