48640
没食子酸乙酯
antioxidant, ≥96.0% (HPLC)
别名:
3,4,5-三羟基苯甲酸乙酯, Progallin A
质量水平
方案
≥96.0% (HPLC)
表单
solid
官能团
ester
SMILES字符串
CCOC(=O)c1cc(O)c(O)c(O)c1
InChI
1S/C9H10O5/c1-2-14-9(13)5-3-6(10)8(12)7(11)4-5/h3-4,10-12H,2H2,1H3
InChI key
VFPFQHQNJCMNBZ-UHFFFAOYSA-N
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一般描述
没食子酸乙酯是没食子酸的乙酯，属于酚类物质。作为一种芳香化合物，常在鞣花酸的酯交换反应合成中用作起始原料。
应用
- 增强创伤愈合：没食子酸乙酯，分离自含羞云实，对促进皮肤伤口愈合具有显著效果。该发现支持它具有皮肤再生的潜在治疗作用(Bhat et al., 2023)。
- 乙醇提取物的药代动力学：研究涉及诃子的乙醇提取物（包括没食子酸乙酯），详述了这些活性物质在大鼠中的药代动力学，提供用于药物应用和药物开发的关键数据(Yao et al., 2023)。
- 民族药理学研究：充分研究覆盆子（一种可提供没食子酸乙酯的植物）的民族植物学、植物化学和药理学，了解传统用途和现代化应用，特别是民族药理学的应用潜力(Tao et al., 2023)。
- 皮肤科应用：在外用软膏剂中添加没食子酸乙酯（来自含羞云实）治疗伤口。说明它在皮肤护理和治疗中的有效作用(Bhat et al., 2022)。
- 神经保护作用：研究景川片（包含没食子酸乙酯）对缺血性脑中风的治疗作用，着重于HIF-1α/EPO/VEGFA信号通路。说明了它在神经保护策略中的重要性(Zhang et al., 2022)。
没食子酸乙酯在可持续绿色化学反应合成喹喔啉类的过程中用作反应试剂。
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Anaïs Izquierdo-Llopart et al.
Foods (Basel, Switzerland), 8(1) (2019-01-13)
Cava is a sparkling wine obtained by a secondary fermentation in its own bottle. Grape skin contains several compounds, such as polyphenols, which act like natural protectors and provide flavor and color to the wines. In this paper, a previously
T Murase et al.
Arteriosclerosis, thrombosis, and vascular biology, 19(6), 1412-1420 (1999-06-11)
Gallates (gallic acid esters) belong to the class of phenolic compounds, which are abundant in red wine. In this study, we show that gallates can inhibit cytokine-induced activation of nuclear factor kappaB (NF-kappaB) and thereby reduce expression of endothelial-leukocyte adhesion
Hydroxide-Catalyzed Ellagic Acid Synthesis from Biobased Ethyl Gallate Using Deep Eutectic Solvents
Misa Mojca C, et al.
ACS sustainable chemistry & engineering, 12, 4007-4016 (2024)
J Wu et al.
Biochemistry and cell biology = Biochimie et biologie cellulaire, 76(4), 661-664 (1999-04-01)
The peroxidation of human erythrocytes induced by peroxyl radical initiator and its inhibition by several gallate esters (e.g., propyl, methyl, ethyl) and Trolox (a more polar analogue of vitamin E) have been studied. The antioxidant activity was determined on erythrocytes
Dan-Dan Tian et al.
Drug metabolism and disposition: the biological fate of chemicals, 46(5), 552-560 (2018-02-23)
Green tea (Camellia sinensis) is a popular beverage worldwide, raising concern for adverse interactions when co-consumed with conventional drugs. Like many botanical natural products, green tea contains numerous polyphenolic constituents that undergo extensive glucuronidation. As such, the UDP-glucuronosyltransferases (UGTs), particularly
实验方案
HPLC Analysis of Polyphenols in Nero d'Avola Red Wine on Discovery® HS C18 (UV 280 nm)
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