48640
没食子酸乙酯
antioxidant, ≥96.0% (HPLC)
别名:
3,4,5-三羟基苯甲酸乙酯, Progallin A
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关于此项目
线性分子式:
3,4,5-(OH)3C6H2COOC2H5
化学文摘社编号:
分子量:
198.17
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
212-608-5
Beilstein/REAXYS Number:
2116014
MDL number:
产品名称
没食子酸乙酯, antioxidant, ≥96.0% (HPLC)
InChI key
VFPFQHQNJCMNBZ-UHFFFAOYSA-N
InChI
1S/C9H10O5/c1-2-14-9(13)5-3-6(10)8(12)7(11)4-5/h3-4,10-12H,2H2,1H3
SMILES string
CCOC(=O)c1cc(O)c(O)c(O)c1
assay
≥96.0% (HPLC)
form
solid
functional group
ester
Quality Level
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Application
- 增强创伤愈合：没食子酸乙酯，分离自含羞云实，对促进皮肤伤口愈合具有显著效果。该发现支持它具有皮肤再生的潜在治疗作用(Bhat et al., 2023)。
- 乙醇提取物的药代动力学：研究涉及诃子的乙醇提取物（包括没食子酸乙酯），详述了这些活性物质在大鼠中的药代动力学，提供用于药物应用和药物开发的关键数据(Yao et al., 2023)。
- 民族药理学研究：充分研究覆盆子（一种可提供没食子酸乙酯的植物）的民族植物学、植物化学和药理学，了解传统用途和现代化应用，特别是民族药理学的应用潜力(Tao et al., 2023)。
- 皮肤科应用：在外用软膏剂中添加没食子酸乙酯（来自含羞云实）治疗伤口。说明它在皮肤护理和治疗中的有效作用(Bhat et al., 2022)。
- 神经保护作用：研究景川片（包含没食子酸乙酯）对缺血性脑中风的治疗作用，着重于HIF-1α/EPO/VEGFA信号通路。说明了它在神经保护策略中的重要性(Zhang et al., 2022)。
没食子酸乙酯在可持续绿色化学反应合成喹喔啉类的过程中用作反应试剂。
General description
没食子酸乙酯是没食子酸的乙酯，属于酚类物质。作为一种芳香化合物，常在鞣花酸的酯交换反应合成中用作起始原料。
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
C Cueva et al.
Letters in applied microbiology, 54(6), 557-563 (2012-03-28)
To investigate the effect of seven wine phenolic compounds and six oenological phenolic extracts on the growth of pathogenic bacteria associated with respiratory diseases (Pseudomonas aeruginosa, Staphylococcus aureus, Moraxella catarrhalis, Enterococcus faecalis, Streptococcus sp Group F, Streptococcus agalactiae and Streptococcus
Steven N Mink et al.
Journal of applied physiology (Bethesda, Md. : 1985), 110(2), 359-374 (2010-11-13)
Although hydrogen peroxide (H2O2) is a well-described reactive oxygen species that is known for its cytotoxic effects and associated tissue injury, H2O2 has recently been established as an important signaling molecule. We previously demonstrated that lysozyme (Lzm-S), a mediator of
Tomoya Takahashi et al.
PloS one, 13(10), e0204856-e0204856 (2018-10-12)
Catechins, biologically active polyphenols in green tea, exhibit various biological activities, such as anticancer and antiviral activities, arising from interactions with functional proteins. However, the molecular details of these interactions remain unclear. In this study, we investigated the interactions between
Xiaobo Wang et al.
Journal of ethnopharmacology, 241, 111801-111801 (2019-03-18)
Rhodiola crenulata, a traditional Tibetan medicine, has shown promise in the treatment of hypobaric hypoxia (HH)-induced brain injury. However, the underlying mechanisms remain unclear. This study investigated the protective effects of R. crenulata aqueous extract (RCAE) on HH-induced brain injury
Facile synthesis of new quinoxalines from ethyl gallate by green chemistry protocol
Rafaely L N, et al.
Tetrahedron Letters, 58, 825-828 (2017)
实验方案
HPLC Analysis of Polyphenols in Nero d'Avola Red Wine on Discovery® HS C18 (UV 280 nm)
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