486825
L-亮氨酸-5,5,5-d3
99 atom % D
别名:
SILAC Amino Acid
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关于此项目
线性分子式:
CH3CH(CD3)CH2CH(NH2)CO2H
化学文摘社编号:
分子量:
134.19
NACRES:
NA.12
PubChem Substance ID:
UNSPSC Code:
12352209
MDL number:
产品名称
L-亮氨酸-5,5,5-d3, 99 atom % D
InChI
1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1/i1D3/t4?,5-
SMILES string
[2H]C([2H])([2H])C(C)C[C@H](N)C(O)=O
InChI key
ROHFNLRQFUQHCH-LONBSJBQSA-N
isotopic purity
99 atom % D
assay
99% (CP)
form
solid
optical activity
[α]25/D +14.5°, c = 2 in 5 M HCl
technique(s)
protein expression: suitable
mp
>300 °C (lit.)
mass shift
M+3
Quality Level
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Application
L-亮氨酸-5,5,5-d3用于使用质谱分析法定量测定蛋白质的含量，也可通过立体定向法合成(2S,4R)-(5,5,5-d3)亮氨酸。
用于通过稳定表位同位素标记 (SITE) 方法，鉴定疫苗开发中病毒诱导的肽。
General description
L-亮氨酸-5,5,5-d3是L-亮氨酸的同位素类似物。
Packaging
该产品可以大包装形式供货，也可按需进行包装。 如需关于价格、供货形式及包装的信息，请联系稳定同位素客户服务。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
美国出口管控产品
此项目有
Gerald W Becker
Briefings in functional genomics & proteomics, 7(5), 371-382 (2008-12-25)
Straightforward methods for the introduction of stable isotopes into proteins with subsequent isolation and purification of the proteins will greatly aid the field of quantitative proteomics. Proteins containing amino acids with one or more of the stable isotopes of deuterium
Hugo D Meiring et al.
Molecular & cellular proteomics : MCP, 5(5), 902-913 (2006-01-25)
Identification of peptides presented in major histocompatibility complex (MHC) class I molecules after viral infection is of strategic importance for vaccine development. Until recently, mass spectrometric identification of virus-induced peptides was based on comparative analysis of peptide pools isolated from
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