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线性分子式:
13CH3COCO2Na
化学文摘社编号:
分子量:
111.04
NACRES:
NA.12
PubChem Substance ID:
UNSPSC Code:
12352106
MDL number:
产品名称
丙酮酸钠-3-13C, 99 atom % 13C
InChI
1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1/i1+1;
SMILES string
[Na+].[13CH3]C(=O)C([O-])=O
InChI key
DAEPDZWVDSPTHF-YTBWXGASSA-M
isotopic purity
99 atom % 13C
assay
99% (CP)
form
solid
technique(s)
bio NMR: suitable
mass spectrometry (MS): suitable
mp
>300 °C (lit.)
mass shift
M+1
storage temp.
2-8°C
Quality Level
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Application
Sodium pyruvate-3-13C is used to study the brain metabolism of exogenous pyruvate.It is also used to investigate the pyruvate metabolism in living cancer cells.
General description
Sodium pyruvate-3-13C is an isotopic analogue of sodium pyruvate.
Packaging
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Sens. 1B
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Chendong Yang et al.
The Journal of biological chemistry, 289(9), 6212-6224 (2014-01-15)
Metabolic reprogramming facilitates cancer cell growth, so quantitative metabolic flux measurements could produce useful biomarkers. However, current methods to analyze flux in vivo provide either a steady-state overview of relative activities (infusion of (13)C and analysis of extracted metabolites) or
Susana Villa Gonzalez et al.
Journal of neurochemistry, 95(1), 284-293 (2005-09-27)
Pyruvate given in large doses may be neuroprotective in stroke, but it is not known to what degree the brain metabolizes pyruvate. Intravenous injection of [3-13C]pyruvate led to dose-dependent labelling of cerebral metabolites so that at 5 min after injection
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Review the 10 steps of glycolysis in the Embden-Meyerhof-Parnas glycolytic pathway. Easily compare reaction stages and buy the enzymes for your life science research.
Isotopic Labeling for NMR Spectroscopy of Biological Solids;
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