质量水平
方案
97%
沸点
118-120 °C/10 mmHg (lit.)
mp
55-59 °C (lit.)
官能团
hydroxyl
SMILES字符串
OCC1CCNCC1
InChI
1S/C6H13NO/c8-5-6-1-3-7-4-2-6/h6-8H,1-5H2
InChI key
XBXHCBLBYQEYTI-UHFFFAOYSA-N
一般描述
4-Piperidinemethanol is a cyclic secondary amine. Its standard molar enthalpies of combustion, sublimation and formation have been determined.
应用
4-Piperidinemethanol may be used in the preparation of:
- N-tert-butoxycarbonyl-4-hydroxymethyl piperidine
- desferrioxamine B (DFO) containing third generation triazine dendrimer
- ethyl 3-(4-(hydroxymethyl)piperidin-1-yl)propanoate (EHMPP)
- 4-(hydroxymethyl)piperidine-1-carbodithioic acid (HL)
- 1-[[(1E)-2-(4-chlorophenyl)ethenyl]sulfonyl]-4-piperidinemethanol
Substrate used in solid-phase organic synthesis of a secondary amine.
警示用语:
Danger
危险声明
危险分类
Skin Corr. 1B
储存分类代码
8A - Combustible corrosive hazardous materials
WGK
WGK 3
闪点(°F)
230.0 °F - closed cup
闪点(°C)
110 °C - closed cup
个人防护装备
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
新产品
Christian A Olsen et al.
Organic letters, 6(12), 1935-1938 (2004-06-05)
[reaction: see text] An expedient solid-phase synthetic approach to secondary and tertiary amines was developed. The protocol employs conversion of resin-bound amino alcohols to the corresponding iodides, followed by iodide displacement with primary or secondary amines or with unprotected amino
Synthesis, spectroscopy, and biological activity of heterobimetallic complexes containing Sn (IV) and Pd (II) with 4-(hydroxymethyl) piperidine-1-carbodithioic acid.
Anwar MT, et al.
Russ. J. Gen. Chem., 83(12), 2380-2385 (2013)
Standard molar enthalpies of formation of 2-, 3-, and 4-piperidinomethanol isomers.
da Silva MAVR and Cabral JITA
The Journal of Chemical Thermodynamics, 38(8), 1008-1012 (2006)
Jongdoo Lim et al.
Bioorganic & medicinal chemistry, 18(15), 5749-5753 (2010-07-10)
The synthesis of a third generation triazine dendrimer, 1, containing multiple, iron-sequestering desferrioxamine B (DFO) groups is described. Benzoylation of the hydroxamic acid groups of DFO and formation of a reactive dichlorotriazine provide the intermediate for reaction with the second
Enzymatic synthesis, thermal and crystalline properties of a poly (β-amino ester) and poly (lactone-co-β-amino ester) copolymers.
Martino L, et al.
Polymer, 53(9), 1839-1848 (2012)
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