49960
1-油酰基-rac-甘油
technical, ~40% (TLC)
别名:
1-(顺-9- 十八烯酰基)-rac-甘油, rac-甘油 1-单油酸酯, DL-α-甘油单油酸酯, 甘油顺-9-十八烯酰基, 甘油单油酸酯
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关于此项目
线性分子式:
CH3(CH2)7CH=CH(CH2)7COOCH2CHOHCH2OH
化学文摘社编号:
分子量:
356.54
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
203-827-7
Beilstein/REAXYS Number:
1728976
MDL number:
InChI key
RZRNAYUHWVFMIP-KTKRTIGZSA-N
InChI
1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-
SMILES string
O=C(CCCCCCC/C=C\CCCCCCCC)OCC(O)CO
description
non-ionic
grade
technical
concentration
~40% (TLC)
impurities
15-40% diglyceride, 15-40% triglyceride
functional group
ester, hydroxyl
Quality Level
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General description
1-油酰基-rac-甘油通常称为甘油单油酸酯（MO）。它是由甘油主链和烃链组成的两亲性分子。
Application
- Bovine Serum Albumin (BSA) Encapsulated in DODAB: MO (1: 2) Liposomes for Targeted Drug Delivery: Development and Characterization：开发含有双十八烷基二甲基溴化铵(DODAB)和1-油酰-外消旋甘油的脂质体用于靶向药物递送(A VAN DIJCK, 2014)。
- An Innovative Nanocarrier for Neuroprotection：研究在DODAB和1-油酰-外消旋甘油(MO)(1:2)组成的纳米载体中包封姜黄素的治疗好处(T Soares, No Date Provided)。
- Supporting Information Light-responsive Molecular Release from Cubosomes using Swell-Squeeze Lattice Control：讨论含1-油酰-外消旋甘油结构的分子释放机制(BE Jones et al., No Date Provided)。
- The Potential of Macroporous Silica—Nanocrystalline Cellulose Combination for Formulating Dry Emulsion Systems with Improved Flow Properties: A DoE Study：详述混有1-油酰-外消旋甘油的干乳系统制剂，用于改善药物应用(M Pohlen, L Pirker, R Dreu, 2021)。
- The Metabolomic Bioenergetic Signature of Opa1-Disrupted Mouse Embryonic Fibroblasts Highlights Aspartate Deficiency：代谢变化分析，提及1-油酰-外消旋甘油等物质的作用(C Bocca et al., 2018)。
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
309.2 °F - closed cup
flash_point_c
154.0 °C - closed cup
ppe
Eyeshields, Gloves, type N95 (US)
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International journal of pharmaceutics, 532(1), 478-490 (2017-09-20)
The current article highlights the application of spray drying technique to produce an ultra-fine powder encapsulating the antihyperlipidemic drug, atorvastatin calcium (ATV). First, ATV was dissolved in an emulsion formulation, and different carriers (pectin, alginate, chitosan HCl and hydroxypropylmethyl cellulose)
Monoolein: a magic lipid?
Kulkarni CV, et al.
Physical Chemistry Chemical Physics, 13(8), 3004-3021 (2011)
Nicholas J Wright et al.
Nature structural & molecular biology, 26(7), 599-606 (2019-06-27)
The human equilibrative nucleoside transporter 1 (hENT1), a member of the SLC29 family, plays crucial roles in adenosine signaling, cellular uptake of nucleoside for DNA and RNA synthesis, and nucleoside-derived anticancer and antiviral drug transport in humans. Because of its
Hyeun Wook Chang et al.
Bioorganic & medicinal chemistry letters, 18(12), 3589-3592 (2008-05-20)
Polyunsaturated fatty acid-derived monoglycerides were characterized from the marine brown alga Sargassum sagamianum, collected from Jeju Island, Korea. A new compound of this structural class was isolated and determined to be 1-octadecatetraenoyl glycerol, by combined spectroscopic methods. Based on the
Xiuhua You et al.
International journal of pharmaceutics, 471(1-2), 276-284 (2014-05-27)
Microemulsions show excellent potential as drug delivery systems, but the surfactants used to prepare them can cause side effects. Researchers have explored various strategies to expand microemulsion area and thereby reduce the surfactant content necessary, but how these strategies affect
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