50515
硬脂醇甘草亭酸酯
≥95.0%
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关于此项目
经验公式（希尔记法）:
C48H82O4
化学文摘社编号:
分子量:
723.16
Beilstein:
7612541
EC 号:
MDL编号:
UNSPSC代码:
12352108
PubChem化学物质编号:
NACRES:
NA.22
方案
≥95.0%
mp
70-77 °C
官能团
ester
hydroxyl
ketone
SMILES字符串
CCCCCCCCCCCCCCCCCCOC(=O)[C@@]1(C)CC[C@]2(C)CC[C@]3(C)C(=CC(=O)[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1
InChI
1S/C48H82O4/c1-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-33-52-42(51)45(5)30-29-44(4)31-32-47(7)36(37(44)35-45)34-38(49)41-46(6)27-26-40(50)43(2,3)39(46)25-28-48(41,47)8/h34,37,39-41,50H,9-33,35H2,1-8H3/t37-,39-,40-,41+,44+,45-,46-,47+,48+/m0/s1
InChI key
WNIFXKPDILJURQ-JKPOUOEOSA-N
一般描述
Stearyl glycyrrhetinate is a stearic acid ester of glycyrrhetinic acid, generally used as a flavoring agent in commercially available cosmetic products.
应用
Stearyl glycyrrhetinate can be used to prepare modified liposomes loaded with norcantharidin and 10-hydroxycamptothecin, which are used as drug delivery systems in cancer therapy.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate, Glycyrrhetinyl Stearate, Stearyl Glycyrrhetinate, Glycyrrhizic Acid, Ammonium Glycyrrhizate, Dipotassium
International Journal of Toxicology, 26, 79-79 (2007)
Jing Zhu et al.
Experimental and therapeutic medicine, 16(3), 1639-1646 (2018-09-07)
In the current study, norcantharidin (NCTD)-loaded liposomes (LIPs) modified with stearyl glycyrrhetinate (SG; SG-NCTD-LIP) were prepared by the ethanol injection method. To increase the drug encapsulation efficiency (EE), the formulation of NCTD-LIP was optimized by single factor test and orthogonal
Ting Zhou et al.
Drug delivery, 26(1), 673-679 (2019-07-04)
10-Hydroxycamptothecin (HCPT) liposomes surface modified with stearyl glycyrrhetinate (SG) were prepared by the film dispersion method. Characterization of the liposomes, including drug release in vitro, pharmacokinetics and tissue distribution, was done. HCPT in plasma and tissues was determined by high-performance
Carmelo Puglia et al.
Journal of cosmetic science, 64(5), 341-353 (2013-10-22)
The aim of this study was to assess the ability of some vehicles (emulsion and emulgel), containing hydrogenated lecithin as penetration enhancer, in increasing the percutaneous absorption of the two model compounds dipotassium glycyrrhizinate (DG) and stearyl glycyrrhetinate (SG). Furthermore
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