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Merck
CN

511129

1-甲基吲哚-2-甲醛

97%

别名:

2-Formyl-1-methylindole, NSC 106285

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关于此项目

经验公式(希尔记法):
C10H9NO
化学文摘社编号:
分子量:
159.18
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
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产品名称

1-甲基吲哚-2-甲醛, 97%

InChI

1S/C10H9NO/c1-11-9(7-12)6-8-4-2-3-5-10(8)11/h2-7H,1H3

SMILES string

Cn1c(C=O)cc2ccccc12

InChI key

IBNGPIOSWCMJGG-UHFFFAOYSA-N

assay

97%

mp

81-85 °C (lit.)

functional group

aldehyde

Quality Level

Application

1-Methylindole-2-carboxaldehyde may be used in the synthesis of indole-based melatonin analog hydrazone derivatives and (E)-5-((benzyloxy)methyl)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-3-((1-methyl-1H-indol-2-yl)methylene)dihydrofuran-2(3H)-one.
Reactant for preparation of:
  • Deazapurine isosteres from acylindoles via pyridine ring annulation
  • 2,4-dichlorocinnamohydroxamic acid analogs for enhancing pharmacokinetics of botulinum neurotoxin serotype A protease inhibitors
  • Tetrahydrocarbazoles via organocatalytic cascade Friedel-Crafts alkylation/Michael addition/aromatization reaction
  • Azides, imines and amines via flow processes of amines and trimethylsilyl azide and aza-Wittig reaction
  • 3-indolylpyridinedicarbonitriles as anti-inflammatory agents
  • Bis(indolyl)methanes as antimicrobial and antioxidant agents

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Sibel Suzen et al.
Journal of enzyme inhibition and medicinal chemistry, 28(6), 1143-1155 (2012-09-22)
Melatonin (MLT) is a strong free-radical scavenger, which protects the body from the effects of oxidants. In recent years, MLT have been described resulting in much attention in the development of synthetic compounds possessing. As a part of our ongoing
Noga Gal et al.
Chembiochem : a European journal of chemical biology, 12(15), 2331-2340 (2012-10-30)
N-methyl-substituted diacylglycerol-indololactones (DAG-indololactones) are newly synthesized effectors of protein kinase C (PKC) isoforms and exhibit substantial selectivity between RasGRP3 and PKCα. We present a comprehensive analysis of membrane interactions and biological activities of several DAG-indololactones. Translocation and binding activity assays

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