519707
8-(甲苯磺酰氨基)喹啉
97%
别名:
N-(8-喹啉基)对甲苯磺酰胺
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关于此项目
经验公式（希尔记法）:
C16H14N2O2S
化学文摘社编号:
分子量:
298.36
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
264159
Assay:
97%
Form:
solid
InChI
1S/C16H14N2O2S/c1-12-7-9-14(10-8-12)21(19,20)18-15-6-2-4-13-5-3-11-17-16(13)15/h2-11,18H,1H3
SMILES string
Cc1ccc(cc1)S(=O)(=O)Nc2cccc3cccnc23
InChI key
ZSMKPYXVUIWTCT-UHFFFAOYSA-N
assay
97%
form
solid
mp
154-158 °C (lit.)
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
E D Gol'dberg et al.
Biulleten' eksperimental'noi biologii i meditsiny, 111(2), 135-137 (1991-02-01)
The injections of diabetogenic drugs to rabbits induced a decrease in zinc and calcium content in B insulocytes dependent on the degree of these cells damage and hyperglycemia. The content of these metals in A insulocytes was not significantly altered
V A Ieshchenko et al.
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 47(2), 66-69 (2001-06-08)
Zinc content in pancreatic islet cells and hippocampus was studied with the aid of highly sensitive selective cytochemical reaction of 8-(p-toluensulfonylamino)-quinoline. It was shown that the factors stimulating B-insulocyte secretory activity induced the decrease of this metal concentrations in the
E D Gol'dberg et al.
Biulleten' eksperimental'noi biologii i meditsiny, 114(11), 491-492 (1992-11-01)
The action of immunosuppressive agent ciclosporin A on the insular apparatus was studied with an original method of cytochemical zinc detection in experiments on mice. The drug was found to lower zinc levels in pancreatic beta-cells. In ciclosporin A pretreatment
J A Lazaris et al.
Endocrinologia experimentalis, 15(2), 99-109 (1981-01-01)
Diabetogenic effects of various analogues of 8-aminoquinoline were studied. Out of 10 compounds investigated only three showed diabetogenic properties: 8-(p-tolylsulfonylamino)-quinoline, 8-(p-benzenesulfonylamino)-quinoline and 8-(p-methylsulfonylamino)-quinoline. After the injection of these compounds a long term persistent hyperglycemia took place in rabbits and also
V D Bovt et al.
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 47(3), 54-57 (2001-08-25)
Alcohol dependence development is accompanied by zinc content decrease in the hippocampus. Young age, repeated physical loads and immobilization are factors, that promote such changes development in more expressed degree.
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