524980
邻苯二甲酸二丁酯（驱蚊叮）
99%
别名:
DBP, 正丁基邻苯二甲酸酯, 邻苯二甲酸二丁基酯
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关于此项目
线性分子式:
C6H4-1,2-[CO2(CH2)3CH3]2
化学文摘社编号:
分子量:
278.34
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
201-557-4
Beilstein/REAXYS Number:
1914064
MDL number:
Assay:
99%
Bp:
340 °C (lit.)
Vapor pressure:
1 mmHg ( 147 °C)
InChI key
DOIRQSBPFJWKBE-UHFFFAOYSA-N
InChI
1S/C16H22O4/c1-3-5-11-19-15(17)13-9-7-8-10-14(13)16(18)20-12-6-4-2/h7-10H,3-6,11-12H2,1-2H3
SMILES string
CCCCOC(=O)c1ccccc1C(=O)OCCCC
vapor density
9.6 (vs air)
vapor pressure
1 mmHg ( 147 °C)
assay
99%
Quality Level
Gene Information
mouse ... Esr1(13982)
autoignition temp.
756 °F
expl. lim.
0.47 %, 236 °F
impurities
≤0.005% Acidity (as Phthalic acid), ≤0.15% water
color
APHA: ≤20
refractive index
n20/D 1.492 (lit.)
pH
7 (20 °C, 10 mg/L)
bp
340 °C (lit.)
mp
−35 °C (lit.)
density
1.043 g/mL at 25 °C (lit.)
functional group
ester
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General description
邻苯二甲酸二丁酯（DBP）最常用作各种家用产品中的增塑剂。在使用或处理这些产品时，它可以浸出和蒸发到环境中。因此，针对其毒性和细胞凋亡效应的研究正在进行。研究还表明，接触高剂量的DBP可能会干扰黄体酮和雌二醇的产生。
Application
增塑剂
signalword
Danger
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
flash_point_f
367.7 °F - open cup
flash_point_c
186.5 °C - open cup
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Classifications
Aquatic Acute 1 - ED ENV 1 - ED HH 1 - Repr. 1B
法规信息
农药列管产品
此项目有
Dibutyl phthalate impairs steroidogenesis and a subset of LH-dependent genes in cultured human mural granulosa cell in vitro.
Adir M
Reproductive Toxicology, 69, 13-18 (2017)
Dibutyl phthalate (DBP)-induced apoptosis and neurotoxicity are mediated via the aryl hydrocarbon receptor (AhR) but not by estrogen receptor alpha (ER?), estrogen receptor beta (ER?), or peroxisome proliferator-activated receptor gamma (PPAR?) in mouse cortical neurons.
Wojtowicz A
Neurotoxicity Research, 31(1), 77-89 (2017)
Linda V Sinclair et al.
Immunometabolism, 2(4), e200029-e200029 (2020-09-04)
Assays to monitor the metabolic state or nutrient uptake capacity of immune cells at a single cell level are increasingly in demand. One assay, used by many immunologists, employs 2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose (2-NBDG), a fluorescent analogue of 2-deoxyglucose (2DG), as a substrate
Damien Hunter et al.
International journal of molecular sciences, 22(8) (2021-05-01)
Xenobiotic exposure during pregnancy and lactation has been linked to perinatal changes in male reproductive outcomes and other endocrine parameters. This pilot study wished to assess whether brief maternal exposure of rats to xenobiotics dibutyl phthalate (DBP) or diethylstilbestrol (DES)
Alin C Dirtu et al.
Environment international, 59, 344-353 (2013-07-31)
Human exposure to chemicals commonly encountered in our environment, like phthalates, is routinely assessed through urinary measurement of their metabolites. A particular attention is given to the specific population groups, such as obese, for which the dietary intake of environmental
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