525057
4-吡唑硼酸频哪醇酯
97%
别名:
4,4,5,5-四甲基-2-(1H-吡唑-4-基)-1,3,2-二氧杂戊硼烷
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关于此项目
线性分子式:
(CH3)4C2O2BC3N2H3
化学文摘社编号:
分子量:
194.04
MDL编号:
UNSPSC代码:
12352103
PubChem化学物质编号:
NACRES:
NA.22
方案
97%
表单
solid
mp
142-146 °C (lit.)
SMILES字符串
CC1(C)OB(OC1(C)C)c2cn[nH]c2
InChI
1S/C9H15BN2O2/c1-8(2)9(3,4)14-10(13-8)7-5-11-12-6-7/h5-6H,1-4H3,(H,11,12)
InChI key
TVOJIBGZFYMWDT-UHFFFAOYSA-N
应用
试剂用于
用于制备含优势骨架吡唑的许多非常重要的治疗酶和激酶的抑制剂的试剂，包括
- Suzuki-Miyaura 交叉耦合
- 钌催化不对称氢化
用于制备含优势骨架吡唑的许多非常重要的治疗酶和激酶的抑制剂的试剂，包括
- VEGF
- 极光
- Rho（岩石）
- Janus 激酶 2 (JAK)
- c-MET
- ALK
- S-亚硝基谷胱甘肽还原酶
- CDC7
- 乙酰辅酶A羧化酶
- 促存活 Bcl-2 蛋白
- 病毒 RNA 依赖性 RNA 聚合酶
- 长链脂肪酸延长酶 6
- PI3
- AKT
- Chk1
- 蛋白激酶 B
法律信息
Boron Molecular 制造
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
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