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Merck
CN

528986

2-氟-4-甲氧基苯甲醛

97%

别名:

2-氟对茴香醛

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线性分子式:
FC6H3(OCH3)CHO
化学文摘社编号:
分子量:
154.14
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
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产品名称

2-氟-4-甲氧基苯甲醛, 97%

InChI

1S/C8H7FO2/c1-11-7-3-2-6(5-10)8(9)4-7/h2-5H,1H3

SMILES string

COc1ccc(C=O)c(F)c1

InChI key

UNWQNFJBBWXFBG-UHFFFAOYSA-N

assay

97%

mp

43-48 °C (lit.)

storage temp.

2-8°C

Application

2-Fluoro-4-methoxybenzaldehyde may be used in the preparation of:
  • fluorine containing 2,4,5-trisubstituted imidazole
  • 1-(2-fluoro-4-methoxyphenyl)-2-propanone
  • 6-(2-fluoro-4-methoxyphenyl)fulvene
  • 10-(2-fluoro-4-methoxyphenyl)-6,7,9,10-tetrahydro-1Hfuro[3,4-b]pyrazolo[3,4-f]quinolin-9-one
  • polyhydroquinoline (PHQ)
  • 3-(2-fluoro-4-methoxyphenyl) acrylic acid methyl ester

General description

2-Fluoro-4-methoxybenzaldehyde is a fluorinated aromatic aldehyde. It can be prepared from 4-bromo-3-fluoroanisole.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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Indium trifluoride: A highly efficient catalyst for the synthesis of fluorine-containing 2, 4, 5-trisubstituted imidazoles under solvent-free conditions.
Reddy MV and Jeong YT.
Journal of Fluorine Chemistry, 142, 45-51 (2012)
Fluorinated derivatives of titanocene Y: synthesis and cytotoxicity studies.
Claffey J, et al.
European Journal of Organic Chemistry, 26, 4074-4082 (2008)
Polystyrene-Supported p-Toluenesulfonic Acid: A New, Highly Efficient, and Recyclable Catalyst for the Synthesis of Hydropyridine Derivatives under Solvent-Free Conditions.
Reddy MV and Jeong YT.
Synlett, 23(20), 2985-2991 (2012)
Synthesis, cytotoxic activity and docking studies of new 4-aza-podophyllotoxin derivatives.
Hatti I, et al.
Medicinal Chemistry Research, 24(8), 3305-3313 (2015)
Synthesis of 1, 3-Bis (hydroxy-halogenophenyl)-propane-1, 3-diamines and their Pt (II) Complexes, Syntheses of the Ligands.
Kammermeier T and Wiegrebe W.
Arch. Pharm. (Weinheim), 327, 547-561 (1994)

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