质量水平
方案
97%
折射率
n20/D 1.374 (lit.)
沸点
50-51 °C (lit.)
密度
0.812 g/mL at 25 °C (lit.)
SMILES字符串
CC1(C)CO1
InChI
1S/C4H8O/c1-4(2)3-5-4/h3H2,1-2H3
InChI key
GELKGHVAFRCJNA-UHFFFAOYSA-N
一般描述
1,2-环氧-2-甲基丙烷是用途多样的环氧单体，可用于制备聚醚基聚合物。所得聚合物可生产水凝胶等聚合材料用于药物递送系统、组织工程和医疗器械。1,2-环氧-2-甲基丙烷还可用于改性现有的聚合物骨架，提高其生物相容性和生物医用性能。
应用
1,2-环氧-2-甲基丙烷可与环状酸酐通过共聚反应合成新型半晶体聚醚。这类聚醚具有优良的热性质，如高熔融温度和力学强度。适于组织工程、外科植入物和生物电子应用。
警示用语：
Danger
危险分类
Carc. 2 - Flam. Liq. 2 - Muta. 2 - Skin Corr. 1C
储存分类代码
3 - Flammable liquids
WGK
WGK 1
闪点(°F)
-26.5 °F
闪点(°C)
-32.5 °C
个人防护装备
Eyeshields, Faceshields, Gloves
法规信息
危险化学品
M Cornet et al.
Chemical research in toxicology, 8(7), 987-992 (1995-10-01)
The biotransformation of 2-methylpropene, a gaseous alkene widely used in industry, was investigated in vitro in liver tissue of rats, mice, and humans. Interspecies comparison revealed that the lowest levels of the primary epoxide metabolite were detected in incubations of
M Cornet et al.
Archives of toxicology, 65(4), 263-267 (1991-01-01)
Until now, no data are available concerning the biotransformation and toxicity of 2-methylpropene (or isobutene), a gaseous alkene widely used in industry (rubber, fuel additives, plastic polymers, adhesives, antioxidants). In this work, the biotransformation of 2-methylpropene (MP) has been studied
Paul R Carlier et al.
The Journal of organic chemistry, 71(4), 1592-1597 (2006-02-14)
Protonated epoxides feature prominently in organic chemistry as reactive intermediates. Herein, we describe 10 protonated epoxides using B3LYP, MP2, and CCSD/6-311++G calculations. Relative to CCSD, B3LYP consistently overestimates the C2-O bond length. Protonated 2-methyl-1,2-epoxypropane is the most problematic species studied
U Jorritsma et al.
Mutagenesis, 10(2), 101-104 (1995-03-01)
2-Methylpropene (isobutene), a gaseous compound widely used in chemical industries, is metabolized to the epoxide 2-methyl-1,2-epoxypropane. The parent compound has previously been shown to be non-mutagenic in a modified Ames test, whereas the epoxide metabolite gave a positive result. In
M Cornet et al.
Mutation research, 271(3), 213-221 (1992-06-01)
The mutagenic properties of 2-methylpropene (MP) and 2-methyl-1,2- epoxypropane (MEP) were investigated in the Salmonella assay. A simple exposure system, consisting of gastight tissue culture flasks, was used. This method has the advantage that the volatile test chemical is present
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