53530
3-氨基二氢噻吩-2-酮 盐酸盐
≥99.0% (AT)
别名:
DL-2-氨基-4-巯基丁酸 1,4-硫内酯 盐酸盐
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关于此项目
经验公式（希尔记法）:
C4H7NOS · HCl
化学文摘社编号:
分子量:
153.63
NACRES:
NA.22
PubChem Substance ID:
eCl@ss:
42021308
UNSPSC Code:
12352100
EC Number:
227-923-3
MDL number:
Beilstein/REAXYS Number:
3689338
Assay:
≥99.0% (AT)
Form:
solid
产品名称
3-氨基二氢噻吩-2-酮 盐酸盐, ≥99.0% (AT)
InChI key
ZSEGSUBKDDEALH-UHFFFAOYSA-N
InChI
1S/C4H7NOS.ClH/c5-3-1-2-7-4(3)6;/h3H,1-2,5H2;1H
SMILES string
Cl[H].NC1CCSC1=O
assay
≥99.0% (AT)
form
solid
loss
≤0.5% loss on drying
mp
202 °C (dec.) (lit.)
~203 °C (dec.)
functional group
thioester
Quality Level
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Application
DL-同型半胱氨酸硫代内酯盐酸盐可用于制备：
- DL-丁硫氨酸
- DL-同型半胱氨酸
- 聚[α,β-(N-2-氨基乙基-dl-天冬酰胺)]-聚[α,β-(N-2-羟乙基-dl-天冬酰胺)]-聚[α,β-(N-3-巯基-1-甲氧基羰基-丙基-dl-天冬酰胺)]共聚物双氯芬酸偶联物（PAHMA-Dic）
- 双[ S-(二甲基胂基)高半胱氨酸]
General description
DL-高半胱氨酸硫代内酯盐酸盐（HTL-HCl）是一种环状氨基酸衍生物，具有根生长抑制活性。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
O W Griffith et al.
The Journal of biological chemistry, 254(16), 7558-7560 (1979-08-25)
Buthionine sulfoximine (S-n-butyl homocysteine sulfoximine), the most potent of a series of analogs of methionine sulfoximine thus far studied (Griffith, O.W., Anderson, M.E., and Meister, A. (1979) J. Biol. Chem. 254, 1205-1210), inhibited gamma-glutamylcysteine synthetase about 20 times more effectively
Kotchakorn Juntapram et al.
Carbohydrate polymers, 90(4), 1469-1479 (2012-09-05)
Novel hydrogel polyelectrolyte complexes (PECs) between the N,N,N,-trimethylchitosan-homocysteine thiolactone (TM-HT-chitosan) and two anionic polymers were investigated. The particles of pure thiolated chitosan and its PECs with alginate and carrageenan were fabricated using the electrospray ionization technique. The hydrogel PEC particles
Hieronim Jakubowski et al.
Advances in clinical chemistry, 55, 81-103 (2011-12-01)
Protein-related homocysteine (Hcy) metabolism produces Hcy-thiolactone, N-Hcy-protein, and N epsilon-homocysteinyl-lysine (N epsilon-Hcy-Lys). Hcy-thiolactone is generated in an error-editing reaction in protein biosynthesis when Hcy is erroneously selected in place of methionine by methionyl-tRNA synthetase. Hcy-thiolactone, an intramolecular thioester, is chemically
Joanna Malinowska et al.
Nutrition (Burbank, Los Angeles County, Calif.), 28(7-8), 793-798 (2012-01-21)
Aronia melanocarpa fruits (Rosaceae) are one of the richest plant sources of phenolic substances, and it has been shown to have various biological activities. Berries of A. melanocarpa (chokeberry) have been supposed to be beneficial for the prevention of cardiovascular
Root-growth inhibition by DL-homocysteine thiolactone and its related compounds.
Inamori Y, et al.
Bioscience, Biotechnology, and Biochemistry, 59(3), 523-525 (1995)
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