Merck
CN
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文件

535303

Sigma-Aldrich

六氟磷酸(7-氮杂苯并三唑-1-氧基)三吡咯烷磷

96%

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别名:
(3-羟基-3H-1,2,3-三唑并[4,5-b]吡啶-O)三-1-吡咯烷基-六氟磷酸磷, PyAOP
经验公式（希尔记法）:
C17H27F6N7OP2
CAS号:
156311-83-0
分子量:
521.38
MDL编号:
MFCD03703417
PubChem化学物质编号:
329757954
NACRES:
NA.22

检测方案

96%

reaction suitability

reaction type: Coupling Reactions

mp

163-168 °C (lit.)

application(s)

peptide synthesis

储存温度

−20°C

SMILES string

F[P-](F)(F)(F)(F)F.C1CCN(C1)[P+](On2nnc3cccnc23)(N4CCCC4)N5CCCC5

InChI

1S/C17H27N7OP.F6P/c1-2-11-21(10-1)26(22-12-3-4-13-22,23-14-5-6-15-23)25-24-17-16(19-20-24)8-7-9-18-17;1-7(2,3,4,5)6/h7-9H,1-6,10-15H2;/q+1;-1

InChI key

CBZAHNDHLWAZQC-UHFFFAOYSA-N

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应用

作为合成以下物质的试剂：
通过点击化学官能团化的环 RGC 五肽
荧光葡萄糖生物探针
ReactIR™ 流式细胞

用于以下反应的试剂：
二硫键工程
杂芳基醚的合成
Grb2-SH2 结构域非磷酸化环肽拮抗剂的构象限制优化

法律信息

经 PE Biosystems 授权销售
ReactIR is a trademark of Mettler-Toledo, Inc.

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H315 - H319 - H335

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

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Si Liu et al.
Journal of proteomics, 181, 225-237 (2018-04-27)
Colorectal cancer (CRC) has become one of the most common cancers worldwide and the fifth most prevalent cancer in China with an upward trend in incidence rates. Altered glycosylation significantly affects the structural and functional changes in immunoglobulin G (IgG)
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Scientific reports, 7, 46206-46206 (2017-04-08)
O-Acetylation of sialic acid in protein N-glycans is an important modification and can occur at either 4-, 7-, 8- or 9-position in various combinations. This modification is usually labile under alkaline reaction conditions. Consequently, a permethylation-based analytical method, which has
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A rapid and sensitive N-glycan profiling strategy for MALDI-MS incorporating the use of deglycosylation with microwave assistance and the co-derivatization of glycosylamine labeling with tris(2,4,6-trimethoxyphenyl)phosphonium acetic acid N-hydroxysuccinimide ester (TMPP-Ac-OSu) and methylamidation has been developed in this work. Notably, highly
Chang Wang et al.
Analytica chimica acta, 1002, 50-61 (2018-01-08)
Quantitative analysis of glycans is an emerging field in glycomic research. Herein we present a rapid and effective dual-labeling strategy, in the combination of isotopic derivatization of N-glycosylamine-based glycans by d0/d5-benzoyl chloride and methylamidation of sialic acids, to relatively quantify
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International journal of medicinal chemistry, 2012, 730239-730239 (2012-01-01)
The purpose of this study is to understand the interactions of some antibacterial cationic amphipathic cyclooctapeptides with calcium(II) and their secondary structural preferences. The thermodynamic parameters associated with calcium(II) interactions, between the antibacterial active cyclooctapeptides (COP 1-6) and those that
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