535834
双（2,2,6,6-四甲基-4-哌啶基）癸二酸酯
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经验公式（希尔记法）:
C28H52N2O4
化学文摘社编号:
分子量:
480.72
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12162002
EC Number:
258-207-9
MDL number:
Quality Level
InChI key
XITRBUPOXXBIJN-UHFFFAOYSA-N
InChI
1S/C28H52N2O4/c1-25(2)17-21(18-26(3,4)29-25)33-23(31)15-13-11-9-10-12-14-16-24(32)34-22-19-27(5,6)30-28(7,8)20-22/h21-22,29-30H,9-20H2,1-8H3
SMILES string
CC1(C)CC(CC(C)(C)N1)OC(=O)CCCCCCCCC(=O)OC2CC(C)(C)NC(C)(C)C2
loss
0.7 wt. % volatility, 150-175°C
mp
82-85 °C (lit.)
transition temp
Tg >350 °C (dec)
solubility
acetone: 19 % (w/w) at 20 °C, ethyl acetate: 24 % (w/w) at 20 °C, methanol: 38 % (w/w) at 20 °C, chloroform: 45 % (w/w) at 20 °C, methylene chloride: 56 % (w/w) at 20 °C, H2O: insoluble <6 ppm at 20 °C
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General description
双（2,2,6,6-四甲基-4-哌啶基）（T770）癸二酸酯是由硝基氧基组成的一种低分子量紫外线（UV）受阻胺光稳定剂（HALS）。它可作为热量调节剂，与聚合物中掺入的酚类抗氧化剂发生反应。
Application
T770可用作塑料中的受阻胺紫外线稳定剂。它可用于药品的生产和包装。氧化钛（TiO2）/T770可作为胺诱导的光稳定剂，用于与聚（氧四亚甲基）二醇（PTMG）合成可循环利用的水基聚氨酯。
signalword
Danger
hcodes
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
>302.0 °F
flash_point_c
> 150 °C
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
H Glossmann et al.
Proceedings of the National Academy of Sciences of the United States of America, 90(20), 9523-9527 (1993-10-15)
A pharmacologically active agent was easily extracted by aqueous or organic solvents from laboratory plastic tubes (Falcon Blue Max) and has been chemically identified as bis(2,2,6,6-tetramethyl-4-piperidyl) sebacate. This compound (approximately 12 micrograms per tube approximately 25 nmol) blocked 1,4-dihydropyridine-sensitive 45Ca2+
Brandon J Hall et al.
Neuroscience letters, 474(2), 84-87 (2010-03-17)
Withdrawal from cocaine use often is associated with anxiety and depressive states. In this study the use-dependent, nicotinic acetylcholine receptor antagonist bis-(2,2,6,6-tetramethyl-4-piperidinyl) sebacate (BTMPS) was studied for its ability to reduce these symptoms in two rat models of anxiety and
V Jackson-Lewis et al.
Brain research, 866(1-2), 197-210 (2000-05-29)
Tinuvin 123, a compound used in the manufacture of plastics, has recently been suggested to possibly cause Parkinson's disease (PD). Herein, we revisited this issue by assessing the effect of Tinuvin 123 on dopaminergic neurons of the substantia nigra following
Brandon J Hall et al.
Neuropharmacology, 58(2), 429-435 (2009-09-24)
The use-dependent, nicotinic acetylcholine receptor antagonist bis-(2,2,6,6-tetramethyl-4-piperidinyl) sebacate (BTMPS) was studied for its potential to reduce the self-administration of nicotine in rats, as well as to reduce context-induced recidivistic-like behavior after a six-week period of cessation. Rats were allowed to
R L Papke et al.
The Journal of pharmacology and experimental therapeutics, 268(2), 718-726 (1994-02-01)
Bis (2,2,6,6-tetramethyl-4-piperidinyl) sebacate (BTMPS; Tinuvin 770), a sterically hindered amine light and radiation stabilizer manufactured by Ciba-Geigy Corp. (Summit, NJ) and used in a wide range of plastics, inhibits nicotinic acetylcholine receptors expressed in Xenopus oocytes in a use-dependent manner.
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