541575
2,4-二氨基-6-羟甲基蝶啶 盐酸盐
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关于此项目
经验公式（希尔记法）:
C7H8N6O ·HCl
化学文摘社编号:
分子量:
228.64
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
InChI
1S/C7H8N6O.ClH/c8-5-4-6(13-7(9)12-5)10-1-3(2-14)11-4;/h1,14H,2H2,(H4,8,9,10,12,13);1H
SMILES string
Cl[H].Nc1nc(N)c2nc(CO)cnc2n1
InChI key
XZHMPUJCSYVIQL-UHFFFAOYSA-N
mp
220 °C (lit.)
functional group
hydroxyl
Quality Level
Application
2,4-Diamino-6-(hydroxymethyl)pteridine hydrochloride may be used in the synthesis of 6-bromomethyl-pteridine-2,4-diamine.
Reactant involved in the synthesis of prodrugs
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Genbin Shi et al.
Bioorganic & medicinal chemistry, 20(1), 47-57 (2011-12-16)
6-Hydroxymethyl-7,8-dihydropterin pyrophosphokinase (HPPK), a key enzyme in the folate biosynthetic pathway, catalyzes the pyrophosphoryl transfer from ATP to 6-hydroxymethyl-7,8-dihydropterin. The enzyme is essential for microorganisms, is absent from humans, and is not the target for any existing antibiotics. Therefore, HPPK
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