Merck
CN

543594

Sigma-Aldrich

5,7-二羟基-4-甲基香豆素

98%

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经验公式(希尔记法):
C10H8O4
CAS号:
分子量:
192.17
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.22

检测方案

98%

mp

296-299 °C (lit.)

SMILES string

CC1=CC(=O)Oc2cc(O)cc(O)c12

InChI

1S/C10H8O4/c1-5-2-9(13)14-8-4-6(11)3-7(12)10(5)8/h2-4,11-12H,1H3

InChI key

QNVWGEJMXOQQPM-UHFFFAOYSA-N

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一般描述

5,7-Dihydroxy-4-methylcoumarin can be obtained by reacting phloroglucinol and ethylacetoacetate via Pechmann condensation in the presence of sulfuric acid.

应用

5,7-Dihydroxy-4-methylcoumarin may be used in the synthesis of pyrano[2,3-h]coumarin derivatives and 5,7-dihydroxy-8-formyl-4-methylcoumarin.

象形图

Exclamation mark

警示用语:

Warning

危险声明

预防措施声明

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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Etil Guzelmeric et al.
Journal of pharmaceutical and biomedical analysis, 132, 35-45 (2016-10-04)
Chamomile tea composed of dried flower heads of Matricaria recutita L. (Asteraceae) is one of the most popular single ingredient herbal teas. Tea industries, spice shops or public bazaars are mostly supplied chamomile as a raw material via cultivation or
Modified coumarins. 27. Ssynthesis and antioxidant activity of 3-substituted 5, 7-dihydroxy-4-methylcoumarins.
Garazd MM, et al.
Chemistry of Natural Compounds, 43(1), 19-23 (2007)
A one-pot, three-component synthesis of new pyrano [2, 3-h] coumarin derivatives.
Karami B, et al.
Tetrahedron Letters, 53(12), 1445-1446 (2012)
Formylation of Benzopyrones. II. Formylation of Hydroxycoumarins with N-Methylformanilide1.
Naik RM and Thakor VM.
The Journal of Organic Chemistry, 22(12), 1630-1633 (1957)
Etil Guzelmeric et al.
Journal of pharmaceutical and biomedical analysis, 107, 108-118 (2015-01-13)
Brewed tea of chamomile flowers (Matricaria recutita L.) (Asteraceae) has been extensively consumed for centuries due to either its pleasant taste or medicinal purposes. On the other hand, the major problem is difficulty in distinguishing the genuine specimen when supplying

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