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Merck
CN

54965

(±)-3-羟基丁酸钠

≥99.0% (NT)

别名:

(±)-3-羟基丁酸 钠盐

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关于此项目

线性分子式:
CH3CH(OH)CH2COONa
化学文摘社编号:
分子量:
126.09
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
205-774-5
Beilstein/REAXYS Number:
4824866
MDL number:
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产品名称

(±)-3-羟基丁酸钠, ≥99.0% (NT)

InChI key

NBPUSGBJDWCHKC-UHFFFAOYSA-M

InChI

1S/C4H8O3.Na/c1-3(5)2-4(6)7;/h3,5H,2H2,1H3,(H,6,7);/q;+1/p-1

SMILES string

[Na+].CC(O)CC([O-])=O

assay

≥99.0% (NT)

mp

167-170 °C

functional group

hydroxyl

Quality Level

Application

(±)-3-羟基丁酸钠已被用于研究,以了解丁酸盐对成纤维细胞生长因子 21(FGF21)的影响,其参与肝脏中的脂肪酸 β-氧化。它可用于制备聚(3-羟基丁酸酯)。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

监管及禁止进口产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Novel synthesis of poly (3-hydroxybutyrate).
Juzwa M and Jedli?ski Z.
Macromolecules, 39(13), 4627-4630 (2006)
Sodium butyrate stimulates expression of fibroblast growth factor 21 in liver by inhibition of histone deacetylase 3.
Li H, et al.
Diabetes, 61(4), 797-806 (2012)
Shengying Pan et al.
Behavioural pharmacology, 31(4), 322-332 (2020-01-03)
β-hydroxybutyrate, a ketone body metabolite, has been shown to suppress depression-like behavior in rodents. In this study, we examined its antidepressive property in acute and chronic administration modes in mice by using forced swim test and tail suspension test. Results
Carolina Akiko Sato Cabral Araújo et al.
PeerJ, 8, e8933-e8933 (2020-04-21)
The end of pregnancy is the period with the highest risk of occurrences of ketosis and pregnancy toxemia due to fat mobilization and increasing non-esterified fatty acids in the liver which are converted in ketone bodies, mainly β-hydroxybutyrate acid (BHB).
Hossein Ghahremani et al.
Galen medical journal, 9, e1831-e1831 (2021-09-02)
Alteration of metabolic pathways in cancer cells can intensely modulate their migration as an important step in invasion and metastasis. Ketogenic diet showed some contradictory results in cancer patients. In this study the impact of metabolic reprogramming of A2780CP as

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