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经验公式(希尔记法):
C16H28N2
化学文摘社编号:
分子量:
248.41
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
97%
InChI
1S/C16H28N2/c1-14(2,3)11-10-12(15(4,5)6)18-13(17-11)16(7,8)9/h10H,1-9H3
SMILES string
CC(C)(C)c1cc(nc(n1)C(C)(C)C)C(C)(C)C
InChI key
VYWSYEDVFVGRGG-UHFFFAOYSA-N
assay
97%
mp
77-80 °C (lit.)
Quality Level
General description
2,4,6-三- 叔 -丁基嘧啶 (TTBP) 是一种非吸湿性空间位阻碱。可由 叔 -丁基甲基酮与 叔 -丁腈反应制得。3 TTBP 是糖基化反应中 2,6-二--叔 -丁基吡啶的合适替代品。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
2, 4, 6-Tri-tert-butylpyrimidine (TTBP): A cost effective, readily available alternative to the hindered base 2, 6-di-tert-butylpyridine and its 4-substituted derivatives in glycosylation and other reactions.
Crich D, et al.
Synthesis, 2001(02), 0323-0326 (2001)
1-Benzenesulfinyl piperidine/trifluoromethanesulfonic anhydride: a potent combination of shelf-stable reagents for the low-temperature conversion of thioglycosides to glycosyl triflates and for the formation of diverse glycosidic linkages.
Crich D and Smith M.
Journal of the American Chemical Society, 123(37), 9015-9020 (2001)
On the mechanism of the reaction between ketones and trifluoromethanesulfonic anhydride. An improved and convenient method for the preparation of pyrimidines and condensed pyrimidines.
Garcia Martinez A, et al.
The Journal of Organic Chemistry, 57(5), 1627-1630 (1992)
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