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Merck
CN

553603

2,3-二溴马来酰亚胺

97%

别名:

3,4-二溴吡咯-2,5-二酮

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关于此项目

经验公式(希尔记法):
C4HBr2NO2
化学文摘社编号:
分子量:
254.86
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
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产品名称

2,3-二溴马来酰亚胺, 97%

InChI

1S/C4HBr2NO2/c5-1-2(6)4(9)7-3(1)8/h(H,7,8,9)

SMILES string

BrC1=C(Br)C(=O)NC1=O

InChI key

BIKSKRPHKQWJCW-UHFFFAOYSA-N

assay

97%

form

solid

mp

228-231 °C (lit.)

functional group

bromo
maleimide

Quality Level

Application

2,3-二溴马来酰亚胺可用于以下合成:
  • 四氢呋喃中的2-溴-3-(1-H-吲哚-3-基)马来酰亚胺与吲哚基溴化镁的反应
  • 2-二溴-3-丙基硫磺酸马来取代与丙硫醇和乙酸钠在甲醇中的反应

General description

2,3-二溴马来酰亚胺是一种环状酰亚胺,基于从头计算和密度泛函理论(DFT)计算得出的偶极矩为0.30德拜。

pictograms

CorrosionExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Skin Corr. 1B - Skin Sens. 1

存储类别

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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A method for preparing water soluble cyclic polymers
Long S, et al.
Reactive functional Polymers, 80, 15-20 (2014)
Jordon Sandland et al.
Bioconjugate chemistry, 30(4), 975-993 (2019-02-16)
This Review aims to highlight key aspects of tetrapyrrole-based antibody-drug conjugates (ADCs) and significant developments in the field since 2010. Many new conjugation methods have been developed and employed in the past decade, and associated with this, there has been
Strong fluorescence enhancement of 2-bromo-3-(1H-indol-3-yl) maleimide upon coordination to a Lewis-acidic metal complex.
Kaletas BK, et al.
Chemical Communications (Cambridge, England), 7, 776-777 (2002)
Polarizability and first-order hyperpolarizability of cyclic imides.
Asghari-Khiavi M, et al.
Journal of Molecular Structure: THEOCHEM, 910(1), 56-60 (2009)
Ting Bai et al.
Macromolecular bioscience, 20(7), e1900438-e1900438 (2020-05-15)
Targeting the distinct cholesterol metabolism of tumor cells is proposed as a novel way to treat tumors. Blocking acyl-CoA cholesterol acyltransferase-1 (ACAT-1) by the inhibitor avasimible (Ava), which elevates intracellular free cholesterol levels, is shown to effectively induce apoptosis. However

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