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Merck
CN

557404

2-氯-4-甲氧基吡啶

97%

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关于此项目

经验公式(希尔记法):
C6H6ClNO
化学文摘社编号:
分子量:
143.57
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
97%
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assay

97%

refractive index

n20/D 1.5400 (lit.)

bp

224-225 °C (lit.)

density

1.258 g/mL at 25 °C (lit.)

SMILES string

COc1ccnc(Cl)c1

InChI

1S/C6H6ClNO/c1-9-5-2-3-8-6(7)4-5/h2-4H,1H3

InChI key

PMTPFBWHUOWTNN-UHFFFAOYSA-N

General description

2-Chloro-4-methoxypyridine can be obtained from the reaction between 2-chloro-4-nitropyridine and sodium methoxide in the presence of dioxane. It can also be prepared starting from 4-methoxy-2(1H)-pyridone and 4-nitropyridine N-oxide.

Application

2-Chloro-4-methoxypyridine may be used to synthesize:
  • 2-(2′,4′-difluorophenyl)-4-methoxypyridine
  • (2-chloro-4-methoxypyridin-3-yl)bis-[2-(methylsulfanyl)pyrimidin-4-yl]methanol
  • (2-chloro-4-methoxypyridin-3-yl)bis-[2-(methylsulfanyl) pyrimidin-4-yl]methyl acetate


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

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分析证书(COA)

Lot/Batch Number

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Syntheses, photoluminescence and electroluminescence of some new blue-emitting phosphorescent iridium (III)-based materials.
Laskar IR, et al.
Polyhedron, 24(2), 189-200 (2005)
Total synthesis of variolin B.
Anderson RJ and Morris JC.
Tetrahedron Letters, 42(49), 8697-8699 (2001)
Regan J Anderson et al.
The Journal of organic chemistry, 70(16), 6204-6212 (2005-07-30)
The total synthesis of the marine alkaloid variolin B has been achieved in 8 steps and 17% overall yield, starting from commercially available 4-chloro-2-methylthiopyrimidine. The key reaction involves the tandem deoxygenation and cyclization of a triarylmethanol using a combination of



全球贸易项目编号

货号GTIN
259470-25G04061838145581
557404-1G04061825744421