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Merck
CN

568562

聚(L-丙交酯-co-己内酯-co-乙交酯)

L-lactide 70 %, average Mn ~50,000 by GPC

别名:

ε-Caprolactone-glycolide-L -lactide copolymer, Poly-L -lactide-co-glycolide-co-ε-caprolactone

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化学文摘社编号:
UNSPSC Code:
12162002
NACRES:
NA.23
MDL number:
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产品名称

聚(L-丙交酯-co-己内酯-co-乙交酯), L-lactide 70 %, average Mn ~50,000 by GPC

form

solid

feed ratio

lactide:caprolactone:glycolide 70:20:10

mol wt

average Mn ~50,000 by GPC

composition

L-lactide, 70%

transition temp

Tg ~28 °C

storage temp.

2-8°C

Quality Level

Features and Benefits

具有生物相容性且可生物降解的聚合物。

Application

Poly(L-lactide-co-caprolactone-co-glycolide) (PLGA-PCL) is a biodegradable block copolymer that may be used as nanoparticle-based drug delivery systems. Electrospun nanofiber blend of PLGA-PCL, phosphorylcholine groups and an antiproliferative (rapamycin)may be used as vascular grafts and prostheses.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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分析证书(COA)

Lot/Batch Number

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Preparation of electrospun poly (L-lactide-co-caprolactone-co-glycolide)/phospholipid polymer/rapamycin blended fibers for vascular application.
Kim H I, et al.
Current Applied Physics, 9(4), e249-e251 (2009)
Novel docetaxel-loaded nanoparticles based on poly (lactide-co-caprolactone) and poly (lactide-co-glycolide-co-caprolactone) for prostate cancer treatment: formulation, characterization, and cytotoxicity studies.
Sanna V, et al.
Nanoscale Research Letters, 6(1), 260-260 (2011)

商品

In the past two decades, tissue engineering and regenerative medicine have become important interdisciplinary fields that span biology, chemistry, engineering, and medicine.

Innovations in polymer technology have had a significant impact on the advancement of novel drug delivery systems.

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