568600
6-(马来酰亚胺基)己酸琥珀酰亚胺酯
98%
别名:
6-马来酰亚氨基己酸 N-琥珀酰亚胺酯, N-(ε-马来酰亚胺己酰氧)琥珀酰亚胺, N-琥珀酰亚胺 6-马来酰亚胺己酸酯, EMCS
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关于此项目
经验公式（希尔记法）:
C14H16N2O6
化学文摘社编号:
分子量:
308.29
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1499815
Assay:
98%
Quality Level
assay
98%
reaction suitability
reagent type: cross-linking reagent
mp
70-73 °C (lit.)
functional group
maleimide, NHS ester, imide
storage temp.
−20°C
SMILES string
O=C(ON(C(CC1)=O)C1=O)CCCCCN2C(C=CC2=O)=O
InChI
1S/C14H16N2O6/c17-10-5-6-11(18)15(10)9-3-1-2-4-14(21)22-16-12(19)7-8-13(16)20/h5-6H,1-4,7-9H2
InChI key
VLARLSIGSPVYHX-UHFFFAOYSA-N
Application
6-马来酰亚胺己酸N-羟基琥珀酰亚胺酯可用于：
- 通过马来酰亚胺硫醇连接反应合成马来酰亚胺活化碳水化合物，用于含半胱氨酸的多肽和蛋白质的位点特异性糖基化。
- 含有马来酰亚胺侧链作为抗肿瘤剂的阿霉素葡糖苷酸前药的合成。
- 将寡核苷酸与底物上的氨基交联以制备DNA微阵列。
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Synthesis and antitumor efficacy of a β-glucuronidase-responsive albumin-binding prodrug of doxorubicin.
Legigan T, et al.
Journal of Medicinal Chemistry, 55(9), 4516-4520 (2012)
Microarray fabrication with covalent attachment of DNA using bubble jet technology.
Okamoto T, et al.
Nature Biotechnology, 18(4), 438-438 (2000)
Synthesis of maleimide-activated carbohydrates as chemoselective tags for site-specific glycosylation of peptides and proteins.
Ni J, et al.
Bioconjugate Chemistry, 14(1), 232-238 (2003)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 568600-500MG | 04061831821703 |