3-噻吩三氟硼酸钾

Potassium 3-thiophenetrifluoroborate is a nucleophilic boronated coupling reagent used to construct a C-C bond by reacting with aryl halides in the presence of a catalyst or under thermal conditions.

Potassium 3-thiophenetrifluoroborate can be used as a reactant to prepare:

• Methyl 3-amino-6-(thien-3-yl)thieno[3,2-b]pyridine-2-carboxylate by reacting with 6-bromothieno[3,2-b]pyridine.
• Thiophene derivatives via Suzuki-Miyaura cross-coupling reaction with aryl halides using palladium complex as a catalyst.
• 2-(Thiophen-3-yl)-3,1,2-benzoxazaborininone and 2-(thiophen-3-yl)-1,3,2-benzoxazaborininone by treating with 2-aminobenzoic acid and 2-hydroxybenzamide, respectively.