600113
L-Arginine-15N4 hydrochloride
98 atom % 15N, 97% (CP)
别名:
SILAC Amino Acid, (S)-(+)-Arginine hydrochloride-15N4, 15N Labeled arginine hydrochloride
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关于此项目
线性分子式:
H215NC(15NH)15NH(CH2)3C(15NH2)CO2H · HCl
化学文摘社编号:
分子量:
214.64
NACRES:
NA.12
PubChem Substance ID:
UNSPSC Code:
12352209
MDL number:
Isotopic purity:
98 atom % 15N
Assay:
≥97% (Chiral Purity), 97% (CP)
Mass shift:
M+4
Form:
solid
Quality Level
mass shift
M+4
InChI
1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m0./s1/i7+1,8+1,9+1,10+1;
SMILES string
Cl[H].[15NH2][C@@H](CCC[15NH]C([15NH2])=[15NH])C(O)=O
InChI key
KWTQSFXGGICVPE-JYJSWXFRSA-N
isotopic purity
98 atom % 15N
assay
≥97% (Chiral Purity), 97% (CP)
form
solid
optical activity
[α]20/D +22°, c = 12 in 10% HCl
technique(s)
bio NMR: suitable, protein expression: suitable
mp
226-230 °C (dec.) (lit.)
相关类别
Application
L-Arginine-15N4 hydrochloride has been used as a supplement for growing rat hybridoma to generate 15N-labeled monoclonal antibody against GPIHBP1 (glycosylphosphatidylinositol-anchored HDL binding protein 1).
General description
Arginine is an amino acid with a basic side group. In liver, arginine is cleaved to ornithine and urea. Isotope labeled amino acids are required for the production of isotopically labeled proteins.
Packaging
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Harvey RA, et al.
Biochemistry (Lippincott's illustrated reviews) (2011)
High-resolution imaging of dietary lipids in cells and tissues by NanoSIMS analysis.
Jiang H, et al.
Journal of Lipid Research, 55, 2156-2166 (2014)
The incorporation of radioactive amino acids into proteins of the microsome fraction of guinea-pig liver at very short time intervals after administration.
Simkin JL and Sutton CR
The Biochemical Journal, 77, 489-492 (1960)
Incorporation of radioactive amino acids into proteins of the microsome fraction of guinea-pig liver in a cell-free system.
SIMKIN JL and WORK TS
The Biochemical Journal, 67, 617-624 (1957)
Isotope labeling for solution and solid-state NMR spectroscopy of membrane proteins.
Verardi R, et al.
Advances in Experimental Medicine and Biology, 992, 35-62 (2012)
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