607851
L-Glutamic acid-13C5,15N
98 atom % 15N, 98 atom % 13C, 95% (CP)
别名:
(S)-2-Aminopentanedioic acid-13C5,15N, 13C and 15N Labeled L-glutamic acid, Glu-13C5,15N
登录 查看组织和合同定价。
选择尺寸
关于此项目
线性分子式:
HO213C(13CH2)213CH(15NH2)13CO2H
化学文摘社编号:
分子量:
153.09
NACRES:
NA.12
PubChem Substance ID:
UNSPSC Code:
12352209
MDL number:
Isotopic purity:
98 atom % 13C
98 atom % 15N
98 atom % 15N
Assay:
95% (CP)
Mass shift:
M+6
Form:
solid
产品名称
L-Glutamic acid-13C5,15N, 98 atom % 15N, 98 atom % 13C, 95% (CP)
InChI
1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1/i1+1,2+1,3+1,4+1,5+1,6+1
SMILES string
[15NH2][13C@@H]([13CH2][13CH2][13C](O)=O)[13C](O)=O
InChI key
WHUUTDBJXJRKMK-UFLWJPECSA-N
isotopic purity
98 atom % 13C
98 atom % 15N
assay
95% (CP)
form
solid
optical activity
[α]25/D +31.0°, c = 2 in 5 M HCl
technique(s)
bio NMR: suitable
mp
205 °C (dec.) (lit.)
mass shift
M+6
Quality Level
相关类别
General description
Glutamic acid is an amino acid with an acidic side group. It works as a proton donor. Decarboxylation of glutamic acid results in the formation of GABA (γ aminobutyric acid), a potent neurotransmitter. Isotope labeled amino acids are required for the production of isotopically labeled proteins.
Packaging
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Kishore K Mahalingan et al.
Nature structural & molecular biology, 27(9), 802-813 (2020-08-05)
Glutamylation, introduced by tubulin tyrosine ligase-like (TTLL) enzymes, is the most abundant modification of brain tubulin. Essential effector proteins read the tubulin glutamylation pattern, and its misregulation causes neurodegeneration. TTLL glutamylases post-translationally add glutamates to internal glutamates in tubulin carboxy-terminal
Fumihiro Eto et al.
Scientific reports, 10(1), 7435-7435 (2020-05-06)
The brain consists of various areas with anatomical features. Neurons communicate with one another via excitatory or inhibitory synaptic transmission. Altered abundance of neurotransmitters, including glutamate and gamma-aminobutyric acid (GABA), in specific brain regions is closely involved in severe neurological
Harvey RA, et al.
Biochemistry (Lippincott's illustrated reviews) (2011)
The incorporation of radioactive amino acids into proteins of the microsome fraction of guinea-pig liver at very short time intervals after administration.
Simkin JL and Sutton CR
The Biochemical Journal, 77, 489-492 (1960)
Garrett RH and Grisham CM
Biochemistry (2012)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持