608130
L-Serine-13C3,15N
98 atom % 15N, 98 atom % 13C, 95% (CP)
别名:
L-Serine-UL-13C,15N
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关于此项目
线性分子式:
HO13CH213CH(15NH2)13CO2H
化学文摘社编号:
分子量:
109.06
NACRES:
NA.12
PubChem Substance ID:
UNSPSC Code:
12352209
MDL number:
产品名称
L-Serine-13C3,15N, 98 atom % 15N, 98 atom % 13C, 95% (CP)
InChI
1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1/i1+1,2+1,3+1,4+1
SMILES string
[15NH2][13C@@H]([13CH2]O)[13C](O)=O
InChI key
MTCFGRXMJLQNBG-UVYXLFMMSA-N
isotopic purity
98 atom % 13C
98 atom % 15N
assay
95% (CP)
form
solid
optical activity
[α]25/D +14.6°, c = 2 in 1 M HCl
technique(s)
bio NMR: suitable
mp
222 °C (dec.) (lit.)
mass shift
M+4
Quality Level
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相关类别
Packaging
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Marc Hennequart et al.
Nature communications, 12(1), 6176-6176 (2021-10-28)
Serine is a non-essential amino acid that is critical for tumour proliferation and depletion of circulating serine results in reduced tumour growth and increased survival in various cancer models. While many cancer cells cultured in a standard tissue culture medium
Methionine Metabolism Shapes T Helper Cell Responses through Regulation of Epigenetic Reprogramming.
Dominic G Roy et al.
Cell metabolism, 31(2), 250-266 (2020-02-06)
Epigenetic modifications on DNA and histones regulate gene expression by modulating chromatin accessibility to transcription machinery. Here we identify methionine as a key nutrient affecting epigenetic reprogramming in CD4+ T helper (Th) cells. Using metabolomics, we showed that methionine is
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