产品名称
D-葡萄糖-12C6, 16O6, 99.9 atom % 16O, 99.9 atom % 12C
InChI key
WQZGKKKJIJFFOK-DVKNGEFBSA-N
InChI
1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
SMILES string
OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
description
13C depleted
18O depleted
isotopic purity
99.9 atom % 12C
99.9 atom % 16O
form
crystalline powder
optical activity
[α]25/D +52.5 to +53°, c = 10 in water + trace NH4OH
mp
150-152 °C (lit.)
solubility
H2O: soluble
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Packaging
该产品可以大包装形式供货，也可按需进行包装。 如需关于价格、供货形式及包装的信息，请联系稳定同位素客户服务。
Application
- glucose metabolism studies in Diabetes research
- Advanced materials research and development
- Analytical method development
- reaction mechanism investigations
- Advanced materials research and development
- Analytical method development
- reaction mechanism investigations
Features and Benefits
Features
Benefits
- High-quality deuterated solvent for NMR.
- Maintains stability under various conditions.
- Optimized for use in spectroscopic studies.
- Ensures minimal interference in analytical methods.
Benefits
- Drives innovation in therapeutic development.
- Reduces time to market for new treatments.
- Increases patient engagement and satisfaction.
- Facilitates collaboration with research institutions.
General description
ᴅ-Glucose-12C6, 16O6 99.9 atom % 16O, 99.9 atom % 12C is a high-purity isotope product with a unique chemical profile that belongs to the class of isotopes. Produced by Sigma-Aldrich, we are committed to providing quality isotope products and a reliable supply chain. Available in industrial and pre-pack quantities.
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Yu-ting Alex Chiang et al.
American journal of physiology. Endocrinology and metabolism, 306(7), E707-E722 (2013-12-26)
p21-Activated protein kinases (PAKs) are centrally involved in a plethora of cellular processes and functions. Their function as effectors of small GTPases Rac1 and Cdc42 has been extensively studied during the past two decades, particularly in the realms of cell
Lars P Bechmann et al.
Journal of hepatology, 56(4), 952-964 (2011-12-17)
It is widely known that the liver is a central organ in lipogenesis, gluconeogenesis and cholesterol metabolism. However, over the last decades, a variety of pathological conditions highlighted the importance of metabolic functions within the diseased liver. As observed in
Ragadeepthi Tunduguru et al.
Biochemical pharmacology, 92(2), 380-388 (2014-09-10)
Skeletal muscle accounts for ∼ 80% of postprandial glucose clearance, and skeletal muscle glucose clearance is crucial for maintaining insulin sensitivity and euglycemia. Insulin-stimulated glucose clearance/uptake entails recruitment of glucose transporter 4 (GLUT4) to the plasma membrane (PM) in a
James C Lo et al.
Cell, 158(1), 41-53 (2014-07-06)
A hallmark of type 2 diabetes mellitus (T2DM) is the development of pancreatic β cell failure, which results in insulinopenia and hyperglycemia. We show that the adipokine adipsin has a beneficial role in maintaining β cell function. Animals genetically lacking
Dov B Ballak et al.
Nature communications, 5, 4711-4711 (2014-09-04)
Cytokines of the IL-1 family are important modulators of obesity-induced inflammation and the development of systemic insulin resistance. Here we show that IL-1 family member IL-37, recently characterized as an anti-inflammatory cytokine, ameliorates obesity-induced inflammation and insulin resistance. Mice transgenic
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