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Merck
CN

634492

吡啶-4-硼酸

90%

别名:

4-吡啶硼酸

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关于此项目

经验公式(希尔记法):
C5H6BNO2
化学文摘社编号:
分子量:
122.92
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352103
MDL number:
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Quality Level

assay

90%

form

solid

mp

>300 °C (lit.)

storage temp.

−20°C

SMILES string

OB(O)c1ccncc1

InChI

1S/C5H6BNO2/c8-6(9)5-1-3-7-4-2-5/h1-4,8-9H

InChI key

QLULGIRFKAWHOJ-UHFFFAOYSA-N

General description

4-吡啶硼酸常用作交叉偶联反应(如Suzuki-Miyaura交叉偶联)中的试剂。

Application

试剂用于
  • 钯催化的 Suzuki-Miyaura 偶联反应
  • 微波辐射下无配体钯催化的 Suzuki 偶联反应

制备过程中使用的试剂
  • HIV-1 蛋白酶抑制剂
  • 潜在的癌症治疗药物,如 PDK1 和蛋白激酶 CK2 抑制剂

Other Notes

含不定量的酸酐


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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商品

Suzuki-Miyaura cross-coupling reaction is extensively used in organic chemistry, polymer science, and pharmaceutical industries.


Ligand-free, PdCl2(PPh3)2-catalyzed, microwave-assisted Suzuki coupling of 1-chloro-3-phenylisoquinoline in the synthesis of diversified 1,3-disubstituted isoquinolines
Prabakaran, K.; Nawaz Khan, F.; Jin, J. S.
Research on Chemical Intermediates, 38, 337-346 (2012)
Jin-Tao Yu et al.
Organic & biomolecular chemistry, 10(7), 1359-1364 (2011-12-20)
An efficient palladium-catalyzed Suzuki-Miyaura coupling method involving the reaction between CTV-Br(3) and a variety of aryl and heteroaryl boronic acids in the presence of indolyl phosphane ligands has been developed. This reaction procedure provided a series of C(3)-symmetric aryl-extended rigid
Jorge Cruz-Huerta et al.
Chemical communications (Cambridge, England), 48(35), 4241-4243 (2012-03-23)
The combination of two heteroaromatic boronic acids with pentaerythritol gave self-complementary tectons which were suitable for the generation of 2D and 3D molecular networks.



全球贸易项目编号

货号GTIN
634492-5G04061832722061
634492-25G04061832905365
634492-1G04061832722047