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线性分子式:
(CH3)2NC10H6SO2NHNH2
化学文摘社编号:
分子量:
265.33
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
251-337-7
Beilstein/REAXYS Number:
2868662
MDL number:
Assay:
98%
产品名称
丹磺酰肼, 98%
InChI
1S/C12H15N3O2S/c1-15(2)11-7-3-6-10-9(11)5-4-8-12(10)18(16,17)14-13/h3-8,14H,13H2,1-2H3
SMILES string
CN(C)c1cccc2c(cccc12)S(=O)(=O)NN
InChI key
KPQYDVAFRDWIBW-UHFFFAOYSA-N
assay
98%
mp
126-130 °C (lit.)
functional group
amine
hydrazine
Quality Level
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Application
丹磺酰肼可呈现荧光,可用于以下用途:
- 通过检测羰基化合物酸催化衍生形成的腙来监测空气污染
- 十二烷基硫酸钠-聚丙烯酰胺凝胶电泳 (SDS-PAGE) 检测分离的糖蛋白
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
"Optimizing a dansylhydrazine (DNSH) based method for measuring airborne acrolein and other unsaturated carbonyls"
Herrington J, et al.
Journal of Environmental Monitoring, 7(10), 969- 976 (2005)
"Analytical reliability of carbonyl compound determination using 1, 5-dansylhydrazine-derivatization"
Binding N, et al.
Fresenius Journal of Analytical Chemistry, 362(03), 270-273 (1998)
"Prestaining of glycoproteins in sodium dodecyl sulfate polyacrylamide gels by dansylhydrazine"
Wang Y, et al.
Proteomics, 14(11), 1322-1327 (2014)
Wenbin Zeng et al.
Bioorganic & medicinal chemistry letters, 18(12), 3573-3577 (2008-05-21)
To develop a small molecule-based tracer for in vivo apoptosis imaging, dansylhydrazone (DFNSH) was synthesized in 93% yield in less than 30 min. The biological evaluation showed that DFNSH selectively binds to paclitaxel-induced apoptotic cancer cells. The high magnification fluorescent
M Tillian et al.
Arzneimittel-Forschung, 46(6), 640-642 (1996-06-01)
A selective cytostatic effect is demonstrated for systemic application of the Michael adduct of crotonal (CAS 4170-30-3) with cysteine (CAS 52-90-4). As in earlier studies, our initial model was the Ehrlich ascites tumor (EAT) in mouse. Tablets containing 150 mg
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