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Merck
CN

640573

环丙磺酰氯

95%

别名:

Cyclopropylsulfonyl chloride

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关于此项目

经验公式(希尔记法):
C3H5ClO2S
化学文摘社编号:
分子量:
140.59
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
95%
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Quality Level

assay

95%

refractive index

n20/D 1.4770 (lit.)

density

1.38 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

ClS(=O)(=O)C1CC1

InChI

1S/C3H5ClO2S/c4-7(5,6)3-1-2-3/h3H,1-2H2

InChI key

PFWWSGFPICCWGU-UHFFFAOYSA-N

Application

Cyclopropanesulfonyl chloride can be used in the synthesis of (1R,2S)-1-amino-2-vinylcyclopropanecarboxylic sulfonamide derivatives, which can serve as building blocks in the preparation of potent hepatitis C virus NS3 protease inhibitors.


pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Skin Corr. 1B

存储类别

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

204.8 °F - closed cup

flash_point_c

96 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

法规信息

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分析证书(COA)

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商品

Sulfonyl chlorides are often chosen as building blocks in medicinal chemistry for their ability to easily react with heterocyclic amines to create complex sulfonamides.

磺酰氯通常被选用为药物化学中的结构单元,因为它们能够容易地与杂环胺反应而产生复合磺酰胺。


"Concise asymmetric synthesis of a (1R, 2S)-1-amino-2-vinylcyclopropanecarboxylic acid-derived sulfonamide and ethyl ester"
Lou Sha, et al.
Organic & Biomolecular Chemistry, 11(39), 6796-6805 (2013)



全球贸易项目编号

货号GTIN
640573-100MG04061832420196
640573-500MG04061832420202