649694
N-乙酰-D-神经氨酸-1,2,3-13C3
≥99 atom % 13C, ≥97% (CP)
别名:
唾液酸-13C3
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
13C3C8H19NO9
化学文摘社编号:
分子量:
312.25
NACRES:
NA.12
PubChem Substance ID:
UNSPSC Code:
12352005
MDL number:
Isotopic purity:
≥99 atom % 13C
Assay:
≥97% (CP)
Mass shift:
M+3
InChI
1S/C11H19NO9/c1-4(14)12-7-5(15)2-11(20,10(18)19)21-9(7)8(17)6(16)3-13/h5-9,13,15-17,20H,2-3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,7+,8+,9+,11?/m0/s1/i2+1,10+1,11+1
SMILES string
CC(=O)N[C@@H]1[C@@H](O)[13CH2][13C](O)(O[C@H]1[C@H](O)[C@H](O)CO)[13C](O)=O
InChI key
SQVRNKJHWKZAKO-JQVNYIDJSA-N
isotopic purity
≥99 atom % 13C
assay
≥97% (CP)
mp
186 °C (lit.)
mass shift
M+3
storage temp.
−20°C
Quality Level
General description
N-乙酰基-D-神经氨酸-1,2,3-13C3 是N-乙酰基-D-神经氨酸的同位素。
Application
N-乙酰基-D-神经氨酸-1,2,3-13C3 可用于通过13C NMR波谱仪定量测定无环酮、酮水合物和烯醇。它也可用于测定作为NANS缺陷患者治疗途径的唾液酸增补剂。
Packaging
该产品可以大包装形式供货，也可按需进行包装。 如需关于价格、供货形式及包装的信息，请联系稳定同位素客户服务。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Christel Tran et al.
Molecular genetics and metabolism reports, 28, 100777-100777 (2021-07-15)
In NANS deficiency, biallelic mutations in the N-acetylneuraminic acid synthase (NANS) gene impair the endogenous synthesis of sialic acid (N-acetylneuraminic acid) leading to accumulation of the precursor, N-acetyl mannosamine (ManNAc), and to a multisystemic disorder with intellectual disability. The aim
Mark D Jankowski et al.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 238, 110336-110336 (2019-09-03)
Understanding variation in physiological traits across taxa is a central question in evolutionary biology that has wide-ranging implications in biomedicine, disease ecology, and environmental protection. Sialic acid (Sia), and in particular, 5-N-acetylneuraminic acid (Neu5Ac), is chemically bound to galactose and
Lilian Dubois et al.
Journal of medicinal chemistry, 63(15), 8231-8249 (2020-07-02)
Sialin, encoded by the SLC17A5 gene, is a lysosomal sialic acid transporter defective in Salla disease, a rare inherited leukodystrophy. It also enables metabolic incorporation of exogenous sialic acids, leading to autoantibodies against N-glycolylneuraminic acid in humans. Here, we identified
Thomas Klepach et al.
Journal of the American Chemical Society, 130(36), 11892-11900 (2008-08-20)
Aqueous solutions of N-acetyl-neuraminic acid (Neu5Ac, 1) labeled with (13)C at C1, C2, and/or C3 were analyzed by (13)C NMR spectroscopy to detect and quantify the acyclic forms (keto, keto hydrate, enol) present at varying pHs. In addition to pyranoses
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持