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651699

1-（1-萘甲基）哌嗪

Name: 1-（1-萘甲基）哌嗪
Brand: ALDRICH

95%

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关于此项目

经验公式（希尔记法）:

C₁₅H₁₈N₂

化学文摘社编号:

40675-81-8

分子量:

226.32

NACRES:

NA.22

PubChem Substance ID:

24883855

UNSPSC Code:

12352100

MDL number:

MFCD01314185

Assay:

95%

Form:

solid

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属性

assay

95%

form

solid

mp

63-67 °C (lit.)

SMILES string

C1CN(CCN1)Cc2cccc3ccccc23

InChI

1S/C15H18N2/c1-2-7-15-13(4-1)5-3-6-14(15)12-17-10-8-16-9-11-17/h1-7,16H,8-12H2

InChI key

HGYDREHWXXUUIS-UHFFFAOYSA-N

说明

pictograms

GHS07,GHS09

signalword

Warning

hcodes

H315,H319,H335,H400

pcodes

P273 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

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Contribution of AcrAB-TolC to multidrug resistance in an Escherichia coli sequence type 131 isolate.

Sabine Schuster et al.

International journal of antimicrobial agents, 50(3), 477-481 (2017-07-12)

Drug efflux by resistance-nodulation-cell division (RND)-type transporters, such as AcrAB-TolC of Escherichia coli, is an important resistance mechanism in Gram-negative bacteria; however, its contribution to multidrug resistance (MDR) in clinical isolates is poorly defined. We inactivated acrB of a sequence

Exposure to Sub-inhibitory Concentrations of the Chemosensitizer 1-(1-Naphthylmethyl)-Piperazine Creates Membrane Destabilization in Multi-Drug Resistant Klebsiella pneumoniae.

João Anes et al.

Frontiers in microbiology, 10, 92-92 (2019-03-01)

Antimicrobial efflux is one of the important mechanisms causing multi-drug resistance (MDR) in bacteria. Chemosensitizers like 1-(1-naphthylmethyl)-piperazine (NMP) can inhibit an efflux pump and therefore can overcome MDR. However, secondary effects of NMP other than efflux pump inhibition are rarely

Contribution of target alteration, protection and efflux pump in achieving high ciprofloxacin resistance in Enterobacteriaceae.

Ram Prosad Chakrabarty et al.

AMB Express, 6(1), 126-126 (2016-12-23)

The study aims at revealing the comprehensive contribution of target alteration, target protection and efflux pump to the development of high level of ciprofloxacin (CIP) resistance in Enterobacteriaceae bacteria of environmental, clinical and poultry origins. Antibiotic susceptibility test was used

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全球贸易项目编号

货号	GTIN
651699-1G	04061826698860
651699-5G	04061833366806