质量水平
方案
97%
表单
solid
mp
310 °C (lit.)
官能团
carboxylic acid
SMILES字符串
OC(=O)c1ccc(OCCCOc2ccc(cc2)C(O)=O)cc1
InChI
1S/C17H16O6/c18-16(19)12-2-6-14(7-3-12)22-10-1-11-23-15-8-4-13(5-9-15)17(20)21/h2-9H,1,10-11H2,(H,18,19)(H,20,21)
InChI key
VBISQLWPGDULSX-UHFFFAOYSA-N
应用
用于聚酐（一类应用于多种给药系统的生物可蚀性聚合物）的结构单元。
警示用语：
Warning
危险声明
危险分类
Aquatic Acute 1 - Skin Sens. 1
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
新产品
此项目有
Urich, K.E. et al.
Macromolecules, 28, 2184-2184 (1995)
A J Domb et al.
Biomaterials, 16(14), 1069-1072 (1995-09-01)
The elimination of a clinically used anticancer biodegradable polymer implant (Gliadel) in the rabbit brain was studied. The implant is composed of N,N-bis(2-chloroethyl)-N-nitrosourea (BCNU) (1.6 wt%) dispersed in a copolyanhydride matrix of 1,3-bis(p-carboxyphenoxypropane) (CPP) and sebacic acid (SA) in a
Sijian Hou et al.
Macromolecular bioscience, 7(5), 620-628 (2007-04-26)
To tailor the erosion rate of polyanhydrides while retaining their surface erosion characteristics, new three-component polyanhydrides of sebacic acid, 1,3-bis(p-carboxyphenoxy)propane and poly(ethylene glycol) were synthesized. The hydrophilicity of the polymer increased and its mechanical strength decreased with increasing PEG content.
Moon Suk Kim et al.
Bio-medical materials and engineering, 15(3), 229-238 (2005-05-25)
p-Carboxyphenoxy propane (CPP) prepolymer consisting of 4 units and sebacic acid (SA) prepolymer consisting of about 10 units were synthesized by reacting CPP and SA in the presence of excess acetic anhydride, respectively. Polyanhydride, poly(CPP-SA) copolymers were copolymerized by a
A J Domb et al.
Biomaterials, 15(9), 681-688 (1994-07-01)
The metabolic disposition and elimination process of the anhydride co-polymer poly[1,3-bis(p-carboxy-phenoxypropane):sebacic acid] 20:80 [P(CPP:Sa)20:80] implanted in the rat brain was studied. Two polymers were prepared, one with [14C]SA and unlabelled CPP, and the other co-polymer with [14C]CPP and unlabelled SA.
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