67070
1-甲基鸟嘌呤
≥95%
别名:
2-氨基-6-羟基-1-甲基嘌呤
方案
≥95%
mp
≥300 °C
SMILES字符串
CN1C(N)=Nc2[nH]cnc2C1=O
InChI
1S/C6H7N5O/c1-11-5(12)3-4(9-2-8-3)10-6(11)7/h2H,1H3,(H2,7,10)(H,8,9)
InChI key
RFLVMTUMFYRZCB-UHFFFAOYSA-N
包装
无底玻璃瓶。内含物装在锥底内插管中。
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
C Hanski et al.
Cell and tissue research, 241(1), 203-206 (1985-01-01)
1-Methylguanine and 7-methylguanine, both metabolic products of tRNA degradation, are known to induce transformation of Chinese hamster fibroblasts in culture. The effects of these compounds on the cell membrane have been studied by the method of Concanavalin A-mediated hemadsorption. 1-Methylguanine
Pål Ø Falnes
Nucleic acids research, 32(21), 6260-6267 (2004-12-04)
The Escherichia coli AlkB protein repairs 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) lesions in DNA and RNA by oxidative demethylation, a reaction requiring ferrous iron and 2-oxoglutarate as cofactor and co-substrate, respectively. Here, we have studied the activity of AlkB proteins
Increases in methylated nucleosides during human pregnancy.
R J Simmonds et al.
Advances in experimental medicine and biology, 165 Pt A, 291-295 (1984-01-01)
H Kaur et al.
The Biochemical journal, 318 ( Pt 1), 21-23 (1996-08-15)
Oxidative DNA damage is thought to be an important contributor to cancer development and to be affected by dietary constituents, so its accurate measurement is important. DNA methylation is recognized as an important mechanism affecting gene expression. In the present
S J Kerr
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 6(2), 115-121 (1985-01-01)
1-Methylguanine and 7-methylguanine are naturally occurring modified purines derived from tRNA, found in elevated levels in the serum and urine of cancer patients. When C3H/10T1/2 clone-8 mouse cells are exposed to low levels of the methylated purines, they are induced
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