679097
(R)-(-)-2-甲基吡咯烷
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关于此项目
经验公式（希尔记法）:
C5H11N
化学文摘社编号:
分子量:
85.15
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352005
MDL number:
InChI
1S/C5H11N/c1-5-3-2-4-6-5/h5-6H,2-4H2,1H3/t5-/m1/s1
SMILES string
C[C@@H]1CCCN1
InChI key
RGHPCLZJAFCTIK-RXMQYKEDSA-N
refractive index
n20/D 1.4353
density
0.842 g/mL at 25 °C (lit.)
storage temp.
2-8°C
Quality Level
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Application
(R)-(−)-2-Methylpyrrolidine, an optically active amine that can be used as a key building block to synthesize:
- 4,5-fused pyridazinone derivatives are applicable as potent histamine H3 receptor antagonists.
- Naphthalenoid histamine H3 receptor antagonist.
- Pyrrolo[2,3-d]pyrimidine derivatives as potent inhibitors of leucine-rich repeat kinase 2.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Flam. Liq. 2 - Skin Corr. 1B
存储类别
3 - Flammable liquids
wgk
WGK 3
flash_point_f
45.0 °F - closed cup
flash_point_c
7.22 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
新产品
此项目有
Identification of pyridazin-3-one derivatives as potent, selective histamine H 3 receptor inverse agonists with robust wake activity
Hudkins, Robert L., et al.
Bioorganic & Medicinal Chemistry Letters, 21.18, 5493-5497 (2011)
Synthesis and evaluation of pyridazinone?phenethylamine derivatives as selective and orally bioavailable histamine H 3 receptor antagonists with robust wake-promoting activity
reddy Dandu, Reddeppa, et al.
Bioorganic & Medicinal Chemistry Letters, 21.21, 6362-6365 (2011)
Synthesis and structure?activity relationships of 4, 5-fused pyridazinones as histamine H 3 receptor antagonists
Tao, Ming, et al.
Bioorganic & Medicinal Chemistry Letters, 21.20, 6126-6130 (2011)
A new class of potent non-imidazole H 3 antagonists: 2-aminoethylbenzofurans
Cowart, Marlon, et al.
Bioorganic & Medicinal Chemistry Letters, 14.3, 689-693 (2004)
Organic Process Research & Development, 11, 1004-1004 (2007)
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