68255
4-甲基-2-氧戊酸
≥98.0% (T)
别名:
2-羰基异己酸, 4-甲基-2-氧基戊酸, α-酮异己酸, 酮亮氨酸
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关于此项目
线性分子式:
(CH3)2CHCH2COCOOH
化学文摘社编号:
分子量:
130.14
NACRES:
NA.22
UNSPSC Code:
12352100
PubChem Substance ID:
EC Number:
212-435-5
Beilstein/REAXYS Number:
1701823
MDL number:
Assay:
≥98.0% (T)
InChI key
BKAJNAXTPSGJCU-UHFFFAOYSA-N
InChI
1S/C6H10O3/c1-4(2)3-5(7)6(8)9/h4H,3H2,1-2H3,(H,8,9)
SMILES string
CC(C)CC(=O)C(O)=O
assay
≥98.0% (T)
refractive index
n20/D 1.431
bp
82-83 °C/11 mmHg (lit.)
mp
8-10 °C
density
1.055 g/mL at 20 °C (lit.)
functional group
carboxylic acid, ketone
storage temp.
2-8°C
Quality Level
General description
4-甲基-2-氧戊酸，又称为α-酮异己酸(KIC)，是亮氨酸的代谢产物。常作为合成砌块制备亮氨酸及其衍生物，并可用于胺化反应和不对称合成反应。 另外，KIC还是Strecker醛类形成的中间体。
Application
- 在人脑酮体代谢中的作用：4-甲基-2-氧戊酸参与创伤性脑损伤患者脑微透析液中酮体代谢的时间模式，说明其在大脑生化通路中的重要作用(Eiden et al., 2019)。
signalword
Danger
hcodes
Hazard Classifications
Skin Corr. 1B
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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