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Merck
CN

68255

4-甲基-2-氧戊酸

≥98.0% (T)

别名:

2-羰基异己酸, 4-甲基-2-氧基戊酸, α-酮异己酸, 酮亮氨酸

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关于此项目

线性分子式:
(CH3)2CHCH2COCOOH
化学文摘社编号:
分子量:
130.14
NACRES:
NA.22
UNSPSC Code:
12352100
PubChem Substance ID:
EC Number:
212-435-5
Beilstein/REAXYS Number:
1701823
MDL number:
Assay:
≥98.0% (T)
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InChI key

BKAJNAXTPSGJCU-UHFFFAOYSA-N

InChI

1S/C6H10O3/c1-4(2)3-5(7)6(8)9/h4H,3H2,1-2H3,(H,8,9)

SMILES string

CC(C)CC(=O)C(O)=O

assay

≥98.0% (T)

refractive index

n20/D 1.431

bp

82-83 °C/11 mmHg (lit.)

mp

8-10 °C

density

1.055 g/mL at 20 °C (lit.)

functional group

carboxylic acid, ketone

storage temp.

2-8°C

Quality Level

General description

4-甲基-2-氧戊酸,又称为α-酮异己酸(KIC),是亮氨酸的代谢产物。常作为合成砌块制备亮氨酸及其衍生物,并可用于胺化反应和不对称合成反应。 另外,KIC还是Strecker醛类形成的中间体。

Application

  • 在人脑酮体代谢中的作用:4-甲基-2-氧戊酸参与创伤性脑损伤患者脑微透析液中酮体代谢的时间模式,说明其在大脑生化通路中的重要作用(Eiden et al., 2019)。

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Skin Corr. 1B

存储类别

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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