692905
N-Ethyl-d5-maleimide
99 atom % D, 98% (CP)
别名:
NEM (ethyl-d5)
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关于此项目
经验公式（希尔记法）:
C6D5H2NO2
化学文摘社编号:
分子量:
130.16
NACRES:
NA.13
PubChem Substance ID:
UNSPSC Code:
12352005
MDL number:
Isotopic purity:
99 atom % D
Assay:
98% (CP)
Mass shift:
M+5
Form:
powder
产品名称
N-Ethyl-d5-maleimide, 99 atom % D, 98% (CP)
InChI key
HDFGOPSGAURCEO-ZBJDZAJPSA-N
SMILES string
[2H]C([2H])([2H])C([2H])([2H])N1C(=O)C=CC1=O
InChI
1S/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3/i1D3,2D2
isotopic purity
99 atom % D
assay
98% (CP)
form
powder
mp
43-46 °C (lit.)
mass shift
M+5
storage temp.
2-8°C
Quality Level
相关类别
Application
N-Ethyl-d5-maleimide can be used:
- To synthesize isotopic silica nanotag by reacting with silica precursor 3-mercaptopropyltrimethoxysilane (MPTMS) for multiplexed ion beam imaging.
- As an isotopic internal standard to determine the ratio of glutathione (GSH) and glutathione disulfide (GSSG) in cultured cells using HPLC-UV and LC-QTOF-MS.
General description
N-Ethyl-d5-maleimide is a deuterated isotope analog of N-ethymaleimide, wherein methylene and methyl protons are replaced by deuterium.
Packaging
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
163.4 °F - closed cup
flash_point_c
73 °C - closed cup
Xueni Sun et al.
Metabolites, 10(7) (2020-07-28)
Glutathione (GSH) and glutathione disulfide (GSSG) are commonly used to assess the oxidative status of a biological system. Various protocols are available for the analysis of GSH and GSSG in biomedical specimens. In this study, we present an optimized protocol
Optimized Protocol for the In Situ Derivatization of Glutathione with N-Ethylmaleimide in Cultured Cells and the Simultaneous Determination of Glutathione/Glutathione Disulfide Ratio by HPLC-UV-QTOF-MS
Sun X, et al.
Metabolites, 10(7), 292-292 (2020)
Stefan Harmsen et al.
Advanced materials technologies, 5(7) (2020-07-15)
High-dimensional profiling of markers and analytes using approaches, such as barcoded fluorescent imaging with repeated labeling and mass cytometry has allowed visualization of biological processes at the single-cell level. To address limitations of sensitivity and mass-channel capacity, a nanobarcoding platform
Isotopically Encoded Nanotags for Multiplexed Ion Beam Imaging
Harmsen S, et al.
Advanced Materials Technologies, 5(7), 2000098-2000098 (2020)
Benjamin Neuditschko et al.
Molecular & cellular proteomics : MCP, 19(3), 478-489 (2020-01-02)
The prediction of metastatic properties from molecular analyses still poses a major challenge. Here we aimed at the classification of metastasis-related cell properties by proteome profiling making use of cutaneous and brain-metastasizing variants from single melanomas sharing the same genetic
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