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2 G
¥1,429.29
About This Item
经验公式（希尔记法）:
C48H40P2
CAS Number:
分子量:
678.78
MDL编号:
UNSPSC代码:
12352005
PubChem化学物质编号:
NACRES:
NA.22
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表单
solid
质量水平
旋光性
[α]20/D -156°, c = 0.5 in benzene
mp
250-255 °C
官能团
phosphine
SMILES字符串
P(c8ccc(cc8)C)(c7ccc(cc7)C)c1c(c6c(cc1)cccc6)c2c3c(ccc2P(c5ccc(cc5)C)c4ccc(cc4)C)cccc3
InChI
1S/C48H40P2/c1-33-13-23-39(24-14-33)49(40-25-15-34(2)16-26-40)45-31-21-37-9-5-7-11-43(37)47(45)48-44-12-8-6-10-38(44)22-32-46(48)50(41-27-17-35(3)18-28-41)42-29-19-36(4)20-30-42/h5-32H,1-4H3
InChI key
IOPQYDKQISFMJI-UHFFFAOYSA-N
1 of 4
此商品 | 615595 | 490865 | 490199 |
|---|---|---|---|
| assay 99% (CP) | assay - | assay 99% (CP) | assay - |
| isotopic purity 99 atom % 13C | isotopic purity 98 atom % D | isotopic purity 99 atom % 13C | isotopic purity 99 atom % 13C |
| mass shift M+2 | mass shift M+2 | mass shift M+2 | mass shift M+2 |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| form solid | form solid | form solid | form solid |
| mp 137-140 °C (lit.) | mp 137-140 °C (lit.) | mp 52-54 °C (lit.) | mp 132-135 °C (dec.) (lit.) |
应用
法律信息
与 Takasago 联合销售，仅供研究使用。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
Kamonpan Sanachai et al.
RSC medicinal chemistry, 12(3), 430-438 (2021-05-29)
The Janus kinase (JAK) and epidermal growth factor receptor (EGFR) have been considered as potential targets for cancer therapy due to their role in regulating proliferation and survival of cancer cells. In the present study, the aromatic alkyl-amino analogs of
Kamonpan Sanachai et al.
ACS omega, 7(37), 33548-33559 (2022-09-27)
Janus kinases (JAKs) are nonreceptor protein tyrosine kinases that play a role in a broad range of cell signaling. JAK2 and JAK3 have been involved in the pathogenesis of common lymphoid-derived diseases and leukemia cancer. Thus, inhibition of both JAK2
Kamonpan Sanachai et al.
ACS omega, 7(37), 33587-33598 (2022-09-27)
Janus kinases (JAKs) are involved in a wide variety of cell signaling associated with T-cell and B-cell mediated diseases. The pathogenesis of common lymphoid-derived diseases and leukemia cancer has been implicated in JAK2 and JAK3. Therefore, to decrease the risk
Kamonpan Sanachai et al.
ACS omega, 5(1), 369-377 (2020-01-21)
Janus kinases (JAKs) are enzymes involved in signaling pathways that affect hematopoiesis and immune cell functions. JAK1, JAK2, and JAK3 play different roles in numerous diseases of the immune system and have also been considered as potential targets for cancer
Chalita Washington et al.
PLoS genetics, 16(6), e1008715-e1008715 (2020-06-20)
Dysregulation of the Ras oncogene in development causes developmental disorders, "Rasopathies," whereas mutational activation or amplification of Ras in differentiated tissues causes cancer. Rabex-5 (also called RabGEF1) inhibits Ras by promoting Ras mono- and di-ubiquitination. We report here that Rabex-5-mediated
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